Myometrial Neoplasia Flashcards
1
Q
What is a leiomyoma?
A
Benign smooth muscle tumour
Aka fibroid
2
Q
Leiomyoma growth is ____ dependent
A
Oestrogen
3
Q
Presentation of leiomyoma
A
Menorrhagia Infertility Mass effect Pain Urinary urgency, frequency or incontinence
4
Q
Investigation of leiomyoma
A
Normal CA125
MRI
Hysteroscopy
Pelvic ultrasound
5
Q
Complications of leiomyoma
A
Leiomyosarcoma
Red degeneration
6
Q
Treatment/management of leiomyoma
A
Mirena coil (<1st line, fibroids <3cm) Symptomatic: NSAIDs, tranexamic acid COC Progestogens GnRH agonists Endometrial ablation Hysteroscopic resection Hysterectomy Uterine artery embolisation Myomectomy
7
Q
How do GnRH agonist work?
A
Shrink fibroids
Suppress feedback loop that causes the release of the hormones the fibroid needs to grow (downregulate)
Creates a medical menopause
Only use for 6mnths
8
Q
What is a leiomyosarcoma?
A
Malignant smooth muscle tumour
9
Q
Presentation of leiomyosarcoma?
A
Abnormal uterine bleeding
Pelvic mass
Pelvic pain
