Myobacterium II Flashcards

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1
Q

Causes chronic pulmonary disease in adults with underlying lung disease (COPD, bronchiectasis)

-Grows best at 42C, found in hot water systems

A

M. xenopi

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2
Q

Causes a rare, extrapulmonary disease in immunocompromised

A

M. xenopi

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3
Q

M. xenopi is classified as a

-Biochemical/molecular ID

A

Scotochromogen

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4
Q

Comprised of three dominant species: M. avium, M. intracellular, M. paratuberculosis

A

Mycobacterium avium Complex (MAC)

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5
Q

What is the most commonly isolated species of MAC?

A

Mycobacterium spp.

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6
Q

MAC is usually classified as

A

Non-chromogenic

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7
Q

Important pathogen in immunocompromised (disseminated disease) AND immunocompetent hosts (pulmonary infection, lymphadentitis)

A

Myobacterium spp.

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8
Q

Important (and sometimes difficult) to distinguish disease vs contamination or colonization in respiratory specimens

A

Mycobacterium avium Complex (MAC)

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9
Q

Seen in post-traumatic, post-surgical, post-injection wound infections

A

Rapid growing mycobacteria (RGM)

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10
Q

Rapid growing mycobacteria (RGM) cause

A

Chronic pulmonary infections

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11
Q

Short, non-branching AFB in clusters, appear as GPR on Gram stain

-Arylsulfatase positive

A

RGM

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12
Q

Often drug resistant, difficult to treat –> species level ID and antibiotic susceptibility tests are important

A

RGM

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13
Q

RGM are classically distinguished biochemically by

A

Iron uptake, salt tolerance, and nitrite reduction

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14
Q

Cannot be cultivated in vitro (armadillo animal model)

A

M. Leprae

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15
Q

Spread from person-person, most likely via nasal secretions

A

M. Leprae

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16
Q

M. Leprae causes single, multiple or widespread anaesthetic skin lesions. It is comprised of which two types?

A

Lepromatous or Tuberculoid