Myelodysplastic Syndrome Flashcards
1
Q
What is Myelodysplastic Syndrome?
A
- Caused by myeloid bone marrow cells not maturing properly and therefore not producing healthy blood cells
2
Q
What do the blood components show?
A
- Anaemia
- Neutropenia
- Thrombocytopenia
3
Q
Who is it typically seen in?
A
- patients above 60 years old
- patients who had previous treatment with chemotherapy and radiotherapy
4
Q
What can myelodysplastic syndrome turn into?
A
- Acute Myeloid Leukaemia
5
Q
How does myelodysplastic syndrome present?
A
- Typically asymptomatic and incidentally diagnosed on a FBC
- Anaemia ( Fatigue, Pallor, SOB)
- Neutropenia ( frequent/ severe infections)
- Thrombocytopenia ( Purpura/ Bleeding)
6
Q
How do you diagnose Myelodysplastic Syndrome?
A
- FBC (abnormal)
- Blood Film (Blast cells)
7
Q
How is the diagnosis confirmed?
A
- Bone Marrow Aspiration and Biopsy
