Myelodysplasia/Acute Leukemia

Question 1

Myelodysplasia

Answer 1

heterogenous group of stem cell disorders characterized by maturation defects & assoc w/ disorderly & ineffective hemaotpoeisis** qualitative & quantitative defects

Question 2

Acute Myeloid Leukemia

Answer 2

Tumor of hematopoeitic progenitors caused by acquired oncogenic mutations that impede differentiation, leading to accumulation of immature blasts in the marrow

Question 3

Promyelocytic Leukemia

Answer 3

type of AML in which abnormal promyelocytes predominate

Question 4

Acute Lymphoblastic Leukemia

Answer 4

systemic, neoblastic proliferation of lymphoblasts within bone marrow and/or in peripheral blood; most common type of leukemia in children