Mycoses Flashcards
Most virulent among human mycotic agents
Coccidiodes immitis
Diagnostic feature of B. dermititidis
Double contoured wall
Broad based bud
MOT of C. immitis
Inhalation of barrel shaped arthroconidia
Produce endospores into the bloodstream
Spherules
Infects what part of the blood. H. capsulatum
Buffy coat layer-WBC
Diseases in C. immitis
Desert fever
San Joaquin Valley fever
desert Rheumatism
Desert bumps
Resides in soil with high nitrogen content
Histoplasma capsulatum
MOT of H. capsulatum
Inhalation of microconidia
H. capsulatum resemble what fungus?
Candida glabrata
Paracoccidiomycoses
South American blastomycosis
Lutz-Splendore-Almeida disease
Brazilian blastomycosis
Paracoccidioidal granuloma
Presence of brown Rhizoids
Rhizopus
Diagnostic feature of Paracoccidioides brasiliensis
Mariner’s wheel appearance of the yeast
Narrow based
Mickey mouse cap appearance of buds
Only dimorphic and pathogenic Penicillium
Penicillium marneffei
Premier caused of yeast infection. Color green in CHROM agar
Candida albicans
Histoplasmosis
Reticuloendothelial cytomycosis Cave disease Spelunkers disease Darling disease Ohio valley fever
Most notorious agents of yeast infections
Candida spp.
Opportunistic mycoses without rhizoids
Mucor
Hyaline saprophyte . Second most isolated fungi
Aspergillus
Fungus ball in the lungs
Aspergillus spp.
Hyalin saprophyte seen in mycotic keratitis
Fusarium
Stain used to detect capsule
India ink
Most notable pathogen
Cryptococcus neoformans
Specie most common isolated from human. Pneumocystis
Pneumocystis jiroveci
Classified with protozoan. Commonly found on rats
Pneumocystis carinii
Teleomorph form of B. dermititidis
Ajellomyces dermititidis
Macroconidia of fusarium
Banana or canoe shaped
Diagnostic feature of H. capsulatum
Tuberculate macroconidia
Causative agent of cryptococcal meningitis
Cryptococcus neoformans
Specimen of choice for Cryptococcus neoformans
Csf
Mode of differentiation for Cryptococcus neoformans
Production of phenol oxidase
Disease cause by malassezia furfur
Tinea versicolor
Inhabits the lungs of many mammals
Pneumocystis
MOT of pneumocystis
Inhalation of cyst
Predictive factor for developing aspergillosis
Neutropenia
Disease cause by B. dermititidis
Gilchrist disease
North American Blastomycosis
Chicago disease
Masters wand or elders wand appearance
Altenaria
Affects the entire system
Systemic mycoses
Fungal diseases that affect only the cornified layer
Superficial mycoses
Appear as pale patches in individual with dark skin
Tinea versicolor
Morphologic characteristic of M.furfur
Spaghetti and meatballs
MOT of M.furfur
Direct contact
Grows only on SDA at room temperature. Forms brown, restricted colonies that remain sterile
Piedraia hortae
Disease caused by P.hortae
Black piedra
The nodules of black piedra contain
Asci with eight ascospore
Thick walled rhomboid cells containing ascospore are seen
Black piedra
Common cause of white piedra
Trichosporon beigelii
Occurs on the hair shaft characterized by a soft mycelial mat surrounding hair of the scalp, face and pubic region
White piedra
Requires lipid for growth
Malassezia furfur
Produce both Arthroconidium and blastoconidium
Trichosporon spp
Produces shiny, moist, yeastlike colonies that start with a brownish coloration that eventually turns olive to greenish black
Hortaea werneckii
Brown to black nonscaly macules that occur most often on the palms of the hnads and soles of the feet
Tinea nigra
Specific conidia seen in tinea nigra
Anneloconidia
General description of dermatophytes
Keratinophilic
Produces macroconidia and microconidia
Dermatophytes
Human dermatophytes
Arthrophilic
Beard hair
Tinea barbae
Glabrous skin
Tinea corporis
Affecting the hand
Tinea manuum
Affecting the nails
Tinea unguium or onychomycosis
Affecting the groin
Tinea cruris or jock itch
Affecting the feet
Tinea pedis
Causative agent of favus
Trichophyton schoenleinii
Spindle shaped macroconidia
Microsporum canis
Fusiform macroconidia
Microsporum gypseum
Microconidia and macroconidia of Trichophyton mentagrophytes
Micro- tear shaoed
Macro- cigar shaped
Clavate or peg shaped microconidia
Trichophyton rubrum
Positive result of hair perforation test
V shaped
Only organism positive for hair baiting test
Microsporum gypseum
Organism who produced red pigment along cornmeal agar and PDA
Trichophyton rubrum
Agricultural workers are often affected
Subcutaneous mycoses
Chronic mycoses of the skin and subcutaneous tissue. Lesion are usually confined in lower extremities
Chromoblastomycosis
Distinguishing or diagnostic feature of chromoblastomycosis
Sclerotic body and cauliflower like surface
Infection that arises at the site of inoculation. Characterized by swelling with characteristics exudate draining to the skin surface through sinus traits
Eumycotic mycetomas
Rosette microconidia
Sporothrix schenckii
Organisms under chromoblastomycosis
Fonsecaea compacta F. Pedrosoi Phialophora verrucosa Cladophialophora carrionii Rhinocladiella aquaspersa
Organism under eumycotic mycetomas
Pseudallescheria boydii Acremonium falciforme Madurella mycetomatis Madurella grisei Exophiala jeanselmi
Mycotic diseases caused by darkly pigmented fungi.. Produces olivaceous to black colonies that ate initially yeast like but become velvety at maturity
Subcutaneous phaeohypomycosis
Distinguishing feature of S.schenckii
Asteroid body
Associated with gardening. Rose handler disease
Sporothrix schenckii
Infection that occurs on the hairs of the scalp. Produces hard dark brown to black gritty nodules that are firmly attached to the hair shaft
Black piedra
Result from traumatic implantation of foreign objects into the deep layers of the skin permitting the fungus to gain entry into the host
Subcutaneous mycoses