DNA Viruses Flashcards
Structure of Adenoviridae
Icosahedral-Naked DS DNA
Family names end with
Viridae
Adenoviridae genus?
Mastadenovirus
Genus names end with
Virus
Structure of Herpesviridae
Icosahedral-Enveloped dsDNA
First isolated from adenoid tissue
Adenoviridae
Structure of Poxviridae
Complex-Enveloped DS DNA
Mode of transmission of Adenoviridae
Direct contact
Fomites
Oral-fecal route
Aerosol
Group of viruses sharing same genetic information and ecological niche
Species
Genital herpes is mainly cause by
HSV 2
HHV4
Epstein Barr virus
CPE: swollen cells with grapelike cluster
Adenoviridae
HHV3
Varicella-zoster virus
Structure of Papillomaviridae
Icosahedral-Naked dsDNA
Can cause latency or lifelong persistent
Herpesviridae
Culture media for Adenoviridae
Human embryonic kidney
Continuous epithelial cell line
HHV5
Cytomegalovirus
Oral herpes is mainly cause by
HHV-1
HHV 1&2 can also cause
Herpes whit low
Eczema herpeticum
The reactivation of chicken pox
Shingles
Genus of HHV 1&2
Simplexvirus
In the diagnosis of this viruses serology is not recommended
HSV 1&2
Specimen for HHV 1&2
Aspirates from secretion
HHV 1&3 mode of transmission
Contact with secretions
Causative agent of shingles
Zoster
Genus of Varicella-zoster virus
Varicellovirus
Shingles can be reactivated if person is
Stress
MOT of VZV
Direct inhalation
Direct contact with lesion
Kissing disease
EBV
Varicella can cause
Chicken pox
Subspecies are designated by?
Numbers
Latency in mononuclear cells
Cytomegalovirus
Culture used in VZV
Human embryonic lung
Vero cells
Latency of shingles reside in?
Dorsal root of cranial nerve ganglia
Diseases associated with EBV
Infectious mononucleosis
Burkitt lymphoma
Hodgkin disease
Nasopharyngeal carcinoma
Specimens in cytomegalovirus
Normally sterile fluids
What makes Paul-Bunnell heterophile antibody test nonspecific
Uses Proteus antigen
Genus of EBV
Lymphocryptovirus
EBV specific serologic test
Anti:
- VCA
- EA IgG
- EA/D
- EA/R
- EBNA
Shed in tears, saliva, urine, stool and breast milk
Cytomegalovirus
MOT of CMV
Close contact with secretions and excretions
Transplacental
HHV8
Kaposi sarcoma herpes virus
Culture used in cytomegalovirus
Diploid fibroblasts cell line
Genus of HHV 6&7
Roseolovirus
AIDS awareness act
RA 8504
Congenital infection can cause
Mental retardation
Deafness
Intellectual impairment
Sixth disease
HHV 6
Genus of HHV 8
Rhadinovirus
Genus of Human Bocavirus
Bocavirus
Most Common cause of congenital infection
Cytomegalovirus
Agent of warts
Papillomavirus
MOT of HHV-8
Sexual contact
Agent of small pox
Variola virus
Common cause of cervical cancer
Papillomaviridae
Largest virus
Poxviridae
Associated with AIDS
Kaposi sarcoma
Genital warts formation
Condylomata acuminate
Smallest of the DNA viruses
Parvoviridae
Genus of Parvovirus B19
Erythrovirus
Agent of fifth disease
Parvovirus B19
Small pox vaccine strain
Vaccinia virus
Cytopathic effect of Papillomavirus
Koilocytes
Serological test in Cytomegalovirus
P65 antigen detection
PCR
Branched DNA
Hybridization assay
Diseases associated with Adenoviridae
Pneumonia Gastroenteritis Keratoconjunctivitis Acute hemorrhagic cystitis Pharyngoconjunctival fever
Screening but non specific test for EBV
Paul-Bunnell heterophile antibody test