Mycoplasma & Ureaplasma

Question 1

General Characteristics

Answer 1

• No cell wall
• Small and pleomorphic
• Cell membrane has sterols
• Slow-growing and fastidious
• Facultative anaerobe

Question 2

Habitat: Mycoplasma Pneumoniae

Answer 2

Oropharynx of humans

Question 3

Habitat: Mycoplasma Hominis

Answer 3

Urogenital tract, 20-50% colonization in women

Question 4

Habitat: Mycoplasma Genitalium

Answer 4

UGT/GIT (pathogenic)

Question 5

Habitat: Ureaplasma Urealyticum

Answer 5

UGT (40-80% colonization in women)

Question 6

Transmisssion General

3 types and species

Answer 6

Inhalation of droplets: M. pneumoniae
Sexual: M. hominis, M. genitalium, U. urealyticum
Mother to child during delivery: M. hominis, U. urealyticum

Question 7

Mycoplasma Pneumoniae: Virulence

Answer 7

• Adhesion proteins: stick to cilia on cells.
• Makes hydrogen peroxide: causes inflammation and cell damage, prolonged cough
  -Community acquired respiratory distress syndrome (CARDS) toxin: cell death

Question 8

Mycoplasma Pneumoniae: Infection

Answer 8

1-4wk incubation
Symptoms: asymptomatic to mild to community
Walking pneumonia, headache, fever, cough

Most common causing pneumonia in hospitalized children

Question 9

Ureaplasma Urealyticum: Infections

Answer 9

10-20 days after sexual transmission
Symptoms: prostatitis, endometritis
Amniotic, newborn infections: stillborn, premature, newborns get pneumonia or meningitis

Question 10

Mycoplasma Hominis Infecton

Answer 10

Postpartum fever
Pelvic inflammatory disease
Salpingitis

Question 11

Mycoplasma Genitalium: Infection

Answer 11

Urethritis, pelvic inflammatory disease, cervicitis

• Resistant to azithromycin