Mycoplasma Pneumoniae

Question 1

Cause what kind of pneumonia

Answer 1

Atypical - why? it is unresponsive to beta lactate antibiotics

Question 2

morphology and features

Answer 2

fried egg colonies; smallest organism capable of growth on cell free media

lacks cell wall

peptidoglycan bound by cell membrane contain sterols

requires cholesterols for growth (add to media for organism to grow)

does not show up on gram stain

Question 3

attachment site

Answer 3

attaches to terminal adhesion protein to carbohydrate receptors on epithelium

Question 4

path

Answer 4

rest epithelial damage due to hydrogen peroxide

RBC damage-hemolytic anemia

inhibits ciliary movement causing prolonged cough

infection limited to resp mucosa that lines the airway, alveoli not involved

Question 5

T or F: alveoli is harmed with infection

Answer 5

false

Question 6

treatment

Answer 6

no penicillin !!

use erythromycin or doxycycline (tetracyclines)

can provide doxycycline as antibiotic prophylaxis for those with sickle cell disease or antibody deficiencies upon exposure

Question 7

Complications

Answer 7

Hemolytic anemia,
Hemolysis (in sickle cell patients),
Steve johnson syndrome (erythma multiforme- type 4 sensitivity,
Raynauds’ phenomenon