Mycology Flashcards
Ingestion of contaminated peanuts and grains causes liver cancer due to AFLUTOXIN
Aspergillus flavus
Liver necrosis due to AMANITIN and PHYLLOIDIN
Amanita mushrooms
Inhalation of the spores causes allergic bronchi pulmonary aspergillosis (IgE-mediated)
Aspergillus fumigatus
Complex carbohydrate cell walls
Chitin
Glucan
Mitochondria
Major membrane sterol
Ergosterol
Study of fungi
Mycology
Infect only superficial keratinization structures
Dermatophytoses
3 important dermatophytes
Microsporum canis
Trichophyton tonsurans
Epidermophyton floccosum
Spectrum of disease ( dermatophytoses)
Tinea pedis Tinea unguium Tinea corporis Tinea cruris (jock itch) Tinea manum Tinea capitis Tinea barbae affects facial hair
Diagnosis (dermatophytoses)
Green fluorescence on Wood’s lamp
Sabourad’s agar: hyphae and conidia
10% KOH: septate hyphae
Superficial skin infection of cosmetic importance
Hypopigmented areas
Spaghetti and meatballs appearance on 10% KOH
Tx: MICONAZOLE
Tinea Versicolor ( Malassezia Furfur)
“AN-AN”
Dimorphic fungus that lives on vegetation
Occurs most often in gardeners, especially those who prune roses
Transmission: thorn prick
Tx: ITRACONAZOLE or POTASSIUM IODIDE
Sporotrichosis (Sporothrix Schenckii)
Dermatophytoses
Malassezia Furfur
Sporothrix Schenckii
Cutaneous mycoses
Dimorphic fungus that exists as a mold in soil and as a spherule in tissue
Endemic in arid regions of the southwestern US and Latin America
Very common in Filipinos living in Latin America and southwestern USA
Inhalation of arthrospores
Coccodoides immitis
Spectrum of disease (coccidiodes immitis)
Valley of fever Influenza like illness Lung infiltrates, adenopathy, or effusions Erythema nodosum (dessert bumps) Arthralgias Meningitis