Mycology Flashcards

1
Q

Study of Fungi

A

Mycology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Eukaryotic, with complex carbohydrate cell walls

A

Fungi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Major membrane sterol; Targeted by imidazole antifungals

A

Ergosterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Require organic carbon

A

Heterotrophic nutrition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Living on dead organic material

A

Saprophytic or saprobic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Fungus living on another organism

A

Parasitic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

2 Basic Forms of Fungi

A

YeastMolds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

2 types of Host Response

A

GranulomatousPyogenic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Causes liver necrosis due to amanitin and phylloidin

A

Amanita mushrooms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ingestion of contaminated peanuts and grains causes liver cancer due to Aflatoxin

A

Aspergillus flavus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Dissolves human cells, allowing visualization

A

KOH preparation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Low pH inhibits the growth of bacteria

A

Sabouraud’s agar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Infect only superficial keratinized structures; Transmission: direct contact, dogs, cats; Chronic infections often located in warm, humid areas of the body; inflames circular border containing papules and vesicles surrounding a clear area of relatively normal skin

A

Dermatophytoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Dermatophyte Infection: Athlete’s foot

A

Tinea pedis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Dermatophyte Infection: Nails

A

Tinea unguium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Dermatophyte Infection: Jock itch

A

Tinea cruris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Dermatophyte Infection: Body

A

Tinea corporis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Dermatophyte Infection: Scalp

A

Tinea capitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Dermatophyte Infection: Facial hair

A

Tinea barbae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Dermatophyte Infection: Hand

A

Tinea manum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Treatment for Dermatophyte Infection

A

Local antifungal creams

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Superficial skin infection of cosmetic importance; Hypopigmented areas; Spaghetti and meatballs appearance on 10% KOH

A

Tinea versicolor (Malassezia furfur)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Treatment for Tinea versicolor

A

Miconazole

24
Q

Dimorphic fungus that lives on vegetation; Occurs most often in gardeners, especially those who prune roses; Transmission: thorn prick

A

Sporotrichosis (Sporothrix schenckii)

25
Treatment of Sporotrichosis
Itraconazole or Potassium iodide
26
Dimorphic fungus that exists as a mold in soil and as a spherule in tissue; Transmission: inhalation of arthrospores; Granuloma in bones and CNS; Dissemination in those who have defective CMI
Coccidioides immitis
27
Influenza-like illness with lung infiltrates, adenopathy or effusions, erythema nodosum (desert bumbs), arthralgias, meningitis
Valley Fever
28
DOC for Valley Fever
DOC: Amphotericin B
29
Dimorphic fungus with 2 types of asexual spores; Grows in soil contaminated with bird droppings (Starling) or bat guano; Transmission: inhalation of airborne microconidia
Histoplasma capsulatum
30
Inhaled microconidia develop into budding yeast inside macrophages; Spread in the liver and spleenn; Dissemination in those who have defective CMI; Closely mimics tuberculosis
Histoplasmosis
31
Can you name 2 great mimickers of PTB?
Histoplasma capsulatumParagonimus westermani
32
DOC of Histoplasmosis
DOC: Amphotericin B
33
Dimorphic fungus with round yeast with broad base bud; Transmission: Inhalation of conidia; Most common cause of fungal pneumonia
Blastomyces dermatitidis
34
Chronic pneumonia, ulcerates granulomas, lytic bone lesions and prostatitis
Blastomycosis
35
DOC for Blastomycosis
DOC: Amphotericin B (Fluconazole- if with brain involvement)
36
Dimorphic fungi with thick yeast with multiple buds in wheel configuration (mariner's wheel/sailor's wheel); Transmission: inhalation of conidia
Paracoccidioides brasiliensis
37
Chronic pneumonia with painful ulcers on mouth and nose
Lutz-Almeida-Splendore Disease
38
Treatment of Lutz-Almeida-Splendore Disease
DOC: Amphotericin B
39
May appear as oval yeast with single bud or as pseudohyphae; Form germ tubes in serum and Chlamydo-spores in culture
Candida albicans
40
Candidiasis in immunocompetent pts
Oral thrushVulvovaginitis (curd-like discharge)Intertrigo (on skin folds)Skin infections (satellite lesions)Onychomycosis
41
Candidiasis in immunocompromised pts
Pseudomembranous esophagitisSubcutaneous nodulesRight-sided endocarditis (in IV drug users)
42
Treatment for Candidiasis
Oropharyngeal candidiasis - Nystatin swish and spitEsophageal candidiasis - Nystatin swish and swallowSkin infections - ClotrimazoleDisseminated Candidiasis - Amphotericin BChemoprophylaxis - Fluconazole
43
Oval yeast with narrow-based bud surrounded by a wide polysaccharide capsule seen in India Ink preparation; Grows abundantly in soil containing bird droppings (especially pigeons)
Cryptococcus neoformans
44
Test for Cryptococcus neoformans
Positive Latex Agglutination Test (CALAS)
45
Asymptomatic lung infection (asymptomatic pneumonia), meningitis, encephalitis
Cryptococcidiosis
46
Treatment of Cryptococcidiosis
DOC: Amphotericin B and Flucytosine (can cross BBB)
47
Exist only as molds; Septate hyphae that form V-shaped (dichotomous) branches; Transmission: inhalation of airborne conidia
Aspergillus fumigatus
48
Fungus ball in lung cavities
Aspergilloma
49
Asthmatic symptoms with expectoration of brownish bronchial plugs
Allergic Bronchopulmonary Aspergillosis (ABPA)
50
Treatment of Aspergillosis
DOC: Amphotericin B
51
Saprophytic molds with nonseptate hyphae with walls and branches at right angles
Rhizopus oryzae and Mucor spp.
52
Rhino-orbital-cerebral Infection with eschar formation; Patients with Diabetic ketoacidosis, burns, or leukemia
Mucormycosis
53
Indeterminate organism; Major surface glycoprotein undergoes programmed rearrangements; Transmission: inhalation of cysts; Cysts in alveoli induce an inflammatory response consisting plasma cells (frothy exudate that blocks oxygen exchange)
Pneumocystis jiroveci
54
Most common AIDS-defining illness; Occurs when CD4<200; Diffuse interstitial pneumonia with ground glass infiltrates bilaterally; 100% mortality
Pneumocystis carinii Pneumonia (PCP)
55
DOC for PCP
Trimethoprim-Sulfamethoxazole