Myasthenia Gravis - Drugs

Question 1

Increase the relative concentration of available acetylcholine at the neuromuscular junction

Answer 1

Pyridostigmine bromide (Mestinon) and Neostigmine bromide (Prostigmin)

Question 2

Decrease the amount of antibody production

Corticosteroids

Answer 2

Immunosuppressive Therapy

Question 3

Administration of human gamma-globulin and show improvement in few days, only lasts for 28 days after infusion

Treats exacerbations

Answer 3

Intravenous Immune Globulin

Question 4

Decrease the circulating anti-acetylcholine receptor

Cyclophosphamide (Cytoxan)

Answer 4

Cytotoxic meds

Question 5

Blood cells and antibody containing plasma are separated, then reinfused back. Temporarily reduces the level of circulating antibodies, can be done OD or every other day

Answer 5

Therapeutic Plasma Exchange (Plasmapheresis)