Myasthenia Gravis Flashcards
Signs/symptoms of Myasthenia gravis
double vision (diplopia), drooping of eyelids (ptosis), difficulty swallowing, skeletal muscle weakness
Medication options for Myasthenia Gravis
cholinesterase inhibitors: neostigmine and pyridostigmine
What are the two “-stigmine” to give for myasthenia gravis?
Neostigmine
Pyridostigmine
MOA for cholinesterase inhibitors
Blocks the cholinesterase enzyme which increases acetylcholine levels
What is Myasthenia gravis
an autoimmune disorder marked by muscle weakness due to acetylcholine receptors being attacked by own body
What is a client experiencing if they have extreme muscle weakness and stop breathing
Myasthenic crisis
Suffix for myasthenia cholinesterase inhibitors
“stigmine”
symptoms of Cholinergic Crisis
SLUDGE and killer B’s
salivation, lacrimation (excessive tearing), urination, diaphoresis/diarrhea, gastrointestinal cramping, emesis
bradycardia, bronchospasm, bronchorrhea
Antidote for cholinergic crisis
atropine
what do you need to assess anytime you give a PO medication for someone who has myathenia gravis
assess their swallowing ability by asking them to take sips of water
what are the symptoms of under medication for someone who has myasthenia gravis?
ptosis and difficulty swallowing
what are the symptoms of over medication for someone who has myasthenia gravis?
excessive salivation