Mutations, Genetics, and Inheritance Questions Flashcards
Recombination occurs between ____ in homologous chromosomes?
Non-sister chromatids
Recombination involves physical exchange of phenotypic information T/F?
False
Chromosomal changes are the same as changes in ploidy numbers T/F?
False
Exchange of genetic information between two non-homologous chromosomes occurs via
Translocations
A change in nucleotide sequence “C to A (a)” produced a STOP codon in the following sequence. How many amino acids are present in the polypeptide?
AGAGGCUAaGUCAAGCUAUGG
2
A change in nucleotide sequence does not produce a change in AA sequence. What are these mutations called?
Silent
Which of the following enzymes methylates DNA in bacteria?
Methyl transferase
UV exposure of nucleic acids produces ___ in the DNA sequence?
Thymine dimers
An allele is the basic unit of transmissible hereditary information T/F?
False
Orthologous genes have different functions T/F?
False
Loss of function mutation results in a ___ allele?
Null
Which of the following is heterozygous dominant?
Gg and gG
From the crossing mentioned, how many gametes with homozygous recessive are possible, per the punnet square?
G/g x g/g
2
During gamete formation the unit factors separate randomly so that each gamete receives both with equal likelihood
False
Genes assort into gametes independently of each other
False
The proofreading repair ability of DNA polymerase enzymes is due to ___
3’-5’ exonuclease activity
In autosomal recessive mutations, the offspring receives the mutant allele from one of the parents T/F?
False
In human pedigrees, unknown sex is denoted by?
Rhombus
A single gene mutation causing several seeming unrelated problems is called?
Pleitrophy
The trait in which is evident in the heterozygous state is called?
Autosomal dominant
Sex linkage is only relevant to organisms with heterogametic sexes in which females and males are genetically identical T/F?
False
In sex linkage, traits determined by the genes on X go back and forth from male to female T/F?
True
X-linked dominant disorders are lethal to females because there is no good allele T/F?
False
Dominance and recessive nature of the allele is relevant in Y-linked inheritance T/F?
False
