Mutated Ras And Cancer Flashcards
1
Q
When the proto-oncogene is mutated…
A
…it transforms into an oncogene
2
Q
What happens when the oncogene is transcribed and translated?
A
Production of hyperactive Ras protein
3
Q
Hyperactivity Effect
A
- Ras protein transmits signals independently of growth factors
- Continuous stimulation of cell cycle
4
Q
Consequence
A
Uncontrolled cell proliferation
5
Q
Contribution to Cancer
A
Unregulated cell growth leads to tumor formation
