DNA Replication

Question 1

Topoisomerase

Answer 1

Unwinds the double helix

Question 2

Helicase

Answer 2

Separates the double stranded DNA by breaking hydrogen bonds between the bases

Question 3

Primase

Answer 3

Synthesizes RNA primer at the 3‘end from the strands of the parental DNA

Question 4

what do RNA primers do?

Answer 4

Mark the starting point of the replication

Question 5

DNA polymerase III

Answer 5

Binds to the RNA primer and adds DNA bases in 5‘ end to 3‘ end direction

Question 6

the lagging strand…

Answer 6

…is build in Okazaki fragments, each part starts with an RNA primer

Question 7

Exonuclease

Answer 7

Removes RNA primers

Question 8

DNA polymerase I

Answer 8

Fills the gaps of where the RNA primers were

Question 9

DNA ligase

Answer 9

Connects neighboring fragments

Question 10

What is the meaning of replication in cell division?

Answer 10

Replication refers to the process by which the genetic material of a cell is duplicated, to ensure that each daughter cell receives an identical copy of the genetic information (S phase of the cell cycle)