MUST KNOWS/ HIGH YIELD CONCEPTS Flashcards
What does the ectoderm give rise to?
Epidermis, melanocytes, nervous system
What structures are derived from the mesoderm?
Fibroblast, blood vessels, muscle, bone, dermis
How do merocrine glands release their contents?
Via exocytosis
What type of glands are eccrine and apocrine glands?
Merocrine glands
What characterizes holocrine glands?
Secretory cells burst
Which type of gland is sebaceous?
Holocrine gland
What type of gland releases contents directly on the skin surface?
Exocrine gland
What is unique about the distribution of sebaceous glands?
Only palms and soles are totally deprived of sebaceous glands
Where are the largest sebaceous glands found?
Nose
What is thalidomide used to treat?
Recurrent or persistent cases of erythema multiforme
What serum bicarbonate level indicates a poor prognosis in epidermal necrolysis?
Below 20 mM
What blood glucose level may indicate severity in epidermal necrolysis?
Above 14 mM
What is the most common complication during the acute phase of epidermal necrolysis?
Sepsis
What is the hallmark of ichthyosis?
Scale
What is ulerythema ophryogenes associated with?
Scarring alopecia on eyebrows; normal scalp and eyelash hair
What condition is characterized by worm-eaten and honeycomb appearance?
Atrophoderma vermiculatum
What are angiokeratomas a cutaneous hallmark of?
Fabry Disease
In what context does pustular PG occur?
Exacerbation of acute IBD (usually UC)
What differentiates vegetative PG from other variants?
Not usually associated with systemic disease
What virus is associated with trichodysplasia spinulosa?
Polyomavirus
What is the most common type of porokeratosis?
Disseminated superficial actinic porokeratosis
What is the primary lesion of pemphigus vulgaris?
Flaccid blister
Which mucous membranes are most affected by pemphigus vulgaris?
Oropharyngeal cavity and nasal mucosa
What is a common presenting sign of pemphigus vulgaris?
Painful mucous membrane erosions