MOST COMMON Flashcards
most common hair shaft disorder associated with breakage
Trichorrhexis nodosa (TN)
Most commonly lost antigen in T-cell lymphoma
CD7
most common infection found in AD
Superficial Staphylococcus aureus infections
most common form of CTCL
Mycosis fungoides
most common infections present in nummular eczema
dental caries and upper respiratory tract infections
what are the most common sites of involvement of LSC
scalp, the nape of the neck, the ankles, the extensor aspects of the extremities, and the anogenital and vulvar regions
most common allergen associated with eyelid dermatitis
gold
accounting for isolated eyelid dermatitis
most common cause of contact allergy in patch-tested patients with cheilitis
fragrance allergens (such as fragrance mix and Myroxylon pereirae [balsam of Peru])
most common class of allergens to cause ACD of the feet
rubber-related chemicals (such as mercaptobenzothiazole, carbamates, thiurams, black rubber mix, and mixed dialkyl thioureas)
most frequently patch test-positive allergen worldwide
Nickel
most common cosmetic allergen
quaternium-15
2 most commonly implicated ACD in topical antibiotics
neomycin and bacitracin
Pustular reactions indicate an irritant reaction and are most commonly encountered with what substances
metallic salts such as potassium dichromate, cobalt, nickel, gold, and copper
Patch testing - most common side effects are expected, such as ___________ at the site of a positive test reaction, and __________from tape application
Patch testing - most common side effects are expected, such as itching at the site of a positive test reaction, and irritation or pruritus from tape application
Patch test reactions that persist for more than 1 month (>30 days) are considered persistent patch test reactions; this occurs most commonly from what?
gold salts in a gold-sensitive patient
most common occupational irritant
Wet work (water or water plus detergent)
best treatment option for ICD
avoidance of irritants
in infantile seb derm, what is the most commonly affected site?
Vertex scalp
most commonly involved sites for ICD given their interaction with the environment and opportunities for irritant exposure
exposed hands
most common presentation of tularemia
ulceroglandular form, where an ulcer arises at the site of inoculation and regional lymphadenopathy develops
most common subtype of PRP
Type I (classic adult)
most common complication of pityriasis lichenoides
Secondary infection
PR is most common in
teenagers and young adults
Herald patch most commonly occurs where?
trunk (50%) followed by the extremities and neck
most common form of oral lesions in pityriasis rosea
Ulcerations
most common areas of involvement of lichen planus
flexural wrists, arms, and legs
Hypertrophic lichen planus occurs most commonly where?
anterior shins and interphalangeal joints
Atrophic lichen planus is most common where?
proximal lower extremity and trunk
Follicular lichen planus occurs most commonly where?
scalp
In mucosal LP, where is the most common site of involvement?
buccal mucosa is the most common site of involvement followed by the tongue and gingiva
What is the most common form of mucosal LP?
reticular form
most common cause of desquamative gingivitis
oral lichen planus
most commonly affected with annular lesions of lichen planus
glans penis
most common findings of nail lichen planus
- diffuse nail involvement with thinning, longitudinal ridging, and distal nail splitting (onychoschizia)
- Pterygium or forward growth of the eponychia with adherence to the proximal nail plate is a classic finding in nail lichen planus involving the matrix.
- Di kasama sa most common yung pterygium!
Oral lichenoid eruptions are most commonly related to what?
dental restorations metals such as mercury, silver, and gold
The most common locations of lichen nitidus
extremities (75% to 77%) and the trunk (9% to 21%)
Most common form of granuloma annulare
annular or arcuate lesion
organs most commonly afflicted in sarcoidosis
lungs
most common presentation of sarcoidosis
papular
most common complaint of sarcoidosis
cosmetic disfigurement
most common presentation of ocular sarcoidosis
uveitis
drug-induced Sweet syndrome—is most commonly associated with?
granulocyte colony-stimulating factor
MC hematologic malignancy associated with sweet syndrome
acute myelogenous leukemia
MC visceral malignancy with sweet syndrome
genitourinary organs, breast, and gastrointestinal tract
most common locations of Giant cellulitis-like Sweet syndrome
upper leg and buttocks
MC infections associated with sweet syndrome
upper respiratory tract (streptococcosis) and the gastrointestinal tract (salmonellosis and yersiniosis)
most common acquired heart disease in children
Kawasaki Disease
Most common complication of pityriasis lichenoides
secondary infection
Pyoderma gangrenosum MC locations depending on the type
- Ulcerative - leg
- Bullous - upper limbs
- Pustular - trunk
- Vegetative - trunk
most common and originally described variant of PG
Ulcerative PG
PG commonly associated with hematologic disease
Bullous PG
most common site for cancer in oral lichen planus
tongue followed by the buccal mucosa, gingiva, and, rarely, the lip
most common locations of giant cellulitis-like Sweet syndrome
upper leg and buttocks
MC subtype of hematologic malignancy associated with PG
acute myeloid leukemia
MC immune dysfunction associated with Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease)
immunoglobulin [Ig] A monoclonal gammopathy
usually the first sign of Schnitzler syndrome and can precede the other symptoms for years
* Recurrent urticarial skin lesions
* second most common symptom is intermittent fever
most common and the first genetically characterized monogenic autoinflammatory disorder
Familial Mediterranean fever (FMF)
most common known inherited periodic fever syndrome
Familial Mediterranean fever (FMF)
2nd - TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PERIODIC SYNDROME
Most common osteoarticular manifestations of SAPHO syndrome
oligoarthritis (affecting sternocostal and sternoclavicular joints, sacroiliac joints, knees, and ankles) and osteitis (anterior chest wall, such as the sternum, clavicle, and ribs, presenting with pain, tenderness, and sometimes swelling over the affected areas)
Mastocytosis is usually associated with what somatic activating mutations
** c-kit **with the 816 codon mutation being most common
most common form of systemic mastocytosis
Indolent systemic mastocytosis
Originally described in children and is the most common skin manifestation of childhood-onset cutaneous mastocytosis
Urticaria Pigmentosa
Mastocytosis - Extracutaneous disease is extremely uncommon in children, but when present, what is tha most frequent?
GI symptoms
GI symptoms in adults ranges from 25% to 70%. Diarrhea is the most common symptom and may result from gastric hypersecretion, increased motility, and/or malabsorption
most common cause of erythema multiforme
HSV
During the acute phase, what is the most common complication of epidermal necrolysis
sepsis
most common form of drug eruptions, accounting for approximately 95% of skin reactions
Exanthematous eruptions, sometimes referred to as morbilliform or maculopapular
what is the most common serologic abnormality in drug-induced lupus
positivity for antinuclear antibodies with a homogenous pattern
most common drugs associated with subacute cutaneous lupus erythematosus
terbinafine, thiazide diuretics, calcium channel blockers, and ranitidine
most common symptom associated with erythema annulare centrifugum
pruritus
MC associated conditions with EAC
superficial dermatophyte infection (13%), pregnancy (5%), thyroid cancer (5%), and medication use (5%)
most common antibiotics used to treat Lyme disease
doxycycline, amoxicillin, and cefuroxime
MC skin finding in trichothiodystrophy
MC skin finding: ichthyosis
2nd - photosensitivity
most common malignancy reported with acquired ichthyosis
Hodgkin disease
most common form of diffuse keratoderma
Epidermolytic PPK (EPPK)
most common type of PPK in the Asian population
Nagashima-type PPK
most common manifestation of plantar keratoderma
focal PPK (FPPK) with calluses over weight-bearing areas
most frequently associated tumor in porokeratosis
SCC
most common skin lesions observed in pemphigus vulgaris
erosions resulting from broken blisters
neoplasms most commonly associated with PNP
Non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), and Castleman disease
most common autoimmune blistering disorder
Bullous pemphigoid
MC locations of BP lesions
flexural surfaces, the lower abdomen, and the thighs
Localized BP most commonly occur where?
lower legs
most common drug that is associated with the development of linear IgA bullous dermatosis
Vancomycin
most common nonimmediate hypersensitivity reaction to vancomycin
Linear IgA bullous dermatosis
Primary lesion of DH
rythematous papule, an urticaria-like plaque, or, most commonly, a vesicle
most common form of epidermolysis bullosa
LOCALIZED EPIDERMOLYSIS BULLOSA SIMPLEX/ Weber-Cockayne subtype of EBS
MC areas affected in Localized EBS
hands and feet being the most common and the scalp being the least common.
most common form of CCLE
classic DLE skin lesion
Mucosal DLE occurs in approximately 25% of patients with CCLE.
What is most frequently affected?
** oral mucosa**
however, nasal, conjunctival, and genital mucosal surfaces can be targeted. In the mouth, the buccal mucosal surfaces are most commonly involved, with the palate, alveolar processes, and tongue being sites of less frequent involvement
most common pulmonary manifestation in DM
ILD
most common radiographic and histologic pattern in DM
nonspecific interstitial pneumonia
most common internal organ involvement in patients suffering from both limited and diffuse SSc
GI involvement
most common pediatric subtype of morphea
Linear morphea
MC subtype of morphea in adults
Circumscribed and generalized
MC Extracutaneous manifestation of morphea patients
Musculoskeletal involvement
most common nail finding in PsA
nail pitting
infectious agents most commonly implicated in reactive arthritis
GI pathogens (Yersinia, Shigella, Salmonella, Campylobacter, and Clostridium difficile) as well as venereal urogenital infection (Chlamydia trachomatis)
most common dermatologic finding in RA
rheumatoid nodule
most commonly identified infection in scleredema
Streptococcal infection
Most common symptoms of xerosis
nonspecific pruritus
most common neurologic manifestation in sjogren syndrome
peripheral axonal polyneuropathies
Most common form cranial neuropathy in Sjogren Syndrome
unilateral trigeminal neuropathy
most common ocular manifestations of relapsing polychondritis
Episcleritis and scleritis
most common causes of secondary anetoderma
acne and varicella
most common systemic conditions associated with adult-onset APD
chronic kidney disease (CKD) and diabetes mellitus (DM)
Ehlers Danlos Syndrome - Defects in what type of collagen gene most commonly cause the classical subtype?
Type V collagen
most common cause of death in vascular EDS
arterial rupture
MC cardiac defect of marfan syndrome
Medial necrosis of the aorta is the most common defect and diffuse dilation of the proximal segment of the ascending aorta with aortic regurgitation often occurs
most common cutaneous manifestations of Marfan syndrome
Lack of subcutaneous fat and the presence of striae, most prominent on the upper chest, arms, thighs, and abdomen
most common ophthalmologic finding of Pseudoxanthoma elasticum
angioid streaks
MC late vascular sequelae in PXE
intermittent claudication
MC location of erythema nodosum
anterior lower legs and ankles
ost common etiology in pediatric cases of EN
streptococcal respiratory tract infections
Erythema induratum most common presentation
ulcerated nodules on the calves, and is associated with MTB infection
EI/NV is seen most commonly in
young to middle-aged women, as dominant as a 9:1 ratio.
most common form of panniculitis
lipodermatosclerosis
most common phenotype to induce panniculitis
A1-antitrypsin - ZZ
most common complication of subcutaneous fat of the newborn
hypercalcemia
most common cutaneous lesion seen in patients with lipodystrophies
acanthosis nigricans in the axillae, groins, neck, and sometimes even on the knuckles, Achilles tendons, and trunk
most common malignancies associated with Peutz jeghers syndrome
GI (small intestine, colorectal, stomach, pancreas)
most common location of melasma
Melasma - malar and mandibular regions, forehead, chin, and upper lip are most commonly affected—centrofacial (63%: forehead, nose, chin, and upper lip); malar (21%: nose and cheeks); and mandibular (16%: ramus mandibulae) patterns are most common
most common complaint in patients with rosacea
Prolonged and frequent flushing is, with erythema
Most common trigger of rosacea
sun exposure
most common cause of industrial acne
cutting oils
most common form of the ectodermal dysplasias.
X-linked hypohidrotic ectodermal dysplasia
most common involvement in chromhidrosis.
Axillary and facial involvement
most commonly affected in fox fordyce disease
axillae
Hidradenitis suppurative-associated anogenital SCC is often associated with high-risk human papillomavirus strains, most commonly what HPV?
human papillomavirus-16
most common type of hair loss
Androgenetic alopecia (AGA)
most common type of AGA in women
FEMALE PATTERN, LUDWIG TYPE; diffuse thinning of the centroparietal region with maintenance of the frontal hair line
most common cause of diffuse hair loss
Telogen effluvium
most common form of hair loss in children
Alopecia areata
most common cause of inflammatory and primary cicatricial alopecia
DLE, together with lichen planopilaris (LPP)
.Some of the most common drugs that cause lichenoid drug eruption
gold, antimalarials, and captopril
Actinic lichenoid drug eruption is confined to sun-exposed sites. The most likely drugs to cause lichenoid drug eruption are quinine and thiazide diuretics
most common form of primary cicatricial alopecia in women of African descent
CCCA
MC hair shaft abnormality in netherton syndrome
trichorrhexis invaginata
most commonly involved areas in hirsutism
upper lip > thighs > lower abdomen > upper back
most common porphyrias to cause hypertrichosis
porphyria cutanea tarda and erythropoietic porphyria
most common color change of the nails
Leukonychia
most common type of ingrown nail
distal–lateral ingrowing of the edge of the big toenail
most common variant of pincer nail
distally increasing curvature
Lichen planus rarely affects the periungual skin, most commonly what part?
proximal matrix and less frequently the nail bed