Musculoskeletal V- Fractures, Pharmacology, Terminology Flashcards
1
Q
Nonopiod agents- Action
A
- nonopiod agents provide analgesia and pain relief, produce anti inflammatory effects, and initiate anti-pyretic (reduces fever) properties
- these drugs promote a reduction of prostaglandin formation that decreases the inflammatory process , decreases uterine contractions, lowers fever, and minimizes impulse formation of pain fibers
2
Q
Nonopiod agents- Indications
A
- mild to moderate pain at various origins; fever, headache, muscle ache, inflammation (except acetaminophen), primary dysmenorrhea, reduction of risk of MI (aspirin only)
3
Q
Nonopiod agents- Side effects
A
- nausea, vomting, vertigo, abdominal pain, GI distress or bleeding, ulcer formation, potential for Reye syndrome in children (aspiring only)
- Reye- A rare but serious condition that causes confusion, swelling in the brain, and liver damage.
4
Q
Nonopiod agents- Implications for PT
A
- patients are at increased risk for masked pain that would allow for movement beyond limitation or false understanding of their level of mobility
- complaints of stomach pain should be taken seriously with subsequent referral to a physician
5
Q
Nonopiod agents- Examples
A
- Tylenol (acetaminophen); Non steroidal anti inflammatories (NSAIDs); Aspirin (acetylsalicylic acid), Aleve (naproxen), Advil (ibuprofen), Celebrex (celecoxib)
6
Q
Opioid agents (Narcotics)- Action
A
- opioid agents provide analgesia for acute severe pain management
- medication stimulates opioid receptors within the CNS to prevent pain impulses from reaching their destination
- certain drugs are also used to assist with dependency and withdrawal symptoms
7
Q
Opioid agents (Narcotics)- Indications
A
- moderate to severe pain of various origins, induction of conscious sedation prior to a diagnostic procedure, management of opioid dependence, relief of severe and persistent cough (codeine)
8
Q
Opioid agents (Narcotics)- Side effects
A
- mood swings, sedation, confusion, vertigo, dulled cognitive function, orthostatic hypotension, constipation, incoordination, physical dependence, tolerance
9
Q
Opioid agents (Narcotics)- Implications for PT
A
- therapist must monitor the patient for potantial side effects, especially signs of respiratory depression
10
Q
Opioid agents (Narcotics)- Examples
A
- Roxanol (Morphine), Demerol (Meperidine), OxyContin (oxycodone), Sublimaze (fetanyl), Paveral (Codeine)
11
Q
Glucocorticoid agents (Corticosteroids)- Action
A
- provide hormonal, anti-inflammatory, and metabolic effects including suppresion of articular and systemic diseases
- these agents reduce inflammation in chronic conditions that can damage healthy tissue through a series of reactions
- vasoconstriction results from stabilizing lysosomal membranes and enhancing the effects of catecholamines
12
Q
Glucocorticoid agents (Corticosteroids)– Indications
A
- replacement therapy for endocrine dysfunction, anti inflammatory and immunosuppresive effects; treatment of rheumatic, respiratory, and various other disorders
13
Q
Glucocorticoid agents (Corticosteroids)- Side effects
A
- muscle strophy, GI distress, glaucoma, adrenocortical suppression, drug-induced Cushing syndrome, weakening with breakdown of supporting tissues (bone, tendon, ligament, skin), mood changes, hypertension
14
Q
Glucocorticoid agents (Corticosteroids)- Implications for PT
A
- therapist must wear a mask when working with patients on glucocorticoid therapy since their immune system is weakened
- patients are at risk for opsteoporosis and muscle wasting
- treatment of an injected joint will require special care due to ligament and tendon laxity or weakening
15
Q
Glucocorticoid agents (Corticosteroids)- Examples
A
- Dermacort (hydrocortisone or cortisol), Cordrol (prednisone), Pediapred (predisolone), Medrol (methylprednisolone), Decadrol (dexamethasone)