Musculoskeletal system Flashcards
Skeletal muscle
Responsible for voluntary movement and is innervated by somatic nervous system
Smooth muscle
Involuntary. Controlled by autonomic nervous system. Capable of more sustained contractions. Exhibits myogenic activity
Cardiac muscle
Contraction is involuntary and is innervated by ANS. Connected by intercalated discs which contain GAP junctions. Exhibit myogenic activity.
Myogenic activity
Contraction without nervous system input
Sliding Filament Model
- Resting Stage; ATP is hydrolyzed
- Ca2+ binds to troponin; myosin binds to actin
- Powerstroke occurs; ADP and Pi dissociate from myosin
- New ATP binds to myosin, causing detachment from actin; ATP hydrolysis causes recocking
Simple twitch vs. Tetanus
Long bone anatomy
Compact bone
Dense and strong; used for protect and support
Spongy bone
Used to support; made of trabeculae which can be remodeled in response to external forces
Bone marrow
Lies within trabeculae and marrow cavities
Red: active, hematopoetic stem cells
Yellow: inactive, composed of fat
Periosteum
Surrounds the bone; has osteogenic properties and is a site for muscle attachment
Osteoblasts vs. Osteoclasts
Osteoblasts build bone
Osteoclasts chew bone
Parathyroid hormone
Released by parathyroid glands in response to low blood Ca2+
Calcitonin
Released by parafollicular cells of the thyroid in response to high blood Ca2+