Immune System Flashcards
Innate immunity
Always active to fight infection
- i.e. skin, lysozyme, phagocytes
Adaptive immunity
Defenses that target a specific pathogen.
Where are white blood cells made?
Bone marrow
Where are B-cells stored and activated?
Spleen.
- B-cells turn into plasma cells to produce antibodies
Where do T-cells mature?
Thymus
The spleen
- Is a storage area for blood
- filters blood and lymph
- Is a site where immune responses can be mounted
Granulocytes
Phil loves his Granny.
- BasoPhil, NeutroPhil, EosinoPhil
Agranulocytes
lympthocytes and monocytes
Interferons
To protects against viruses, cells produces these to interfere with viral replication and dispersion
MHC (major histocompatibility complex)
Presents antigens that either originate inside or outside of the cell.
Immunoglobulins
Antibodies. Can be displayed on cell surface or float freely.
Y-shaped molecules that bind to antigens. Can induce:
opsonization, agglutination, neutralization, degranulation
Helper T-Cells
Coordinate the immune response and recruit other immune cells.
CD4+ - most effective against bacterial, fungal, parasitic infections; MHC-2
CD8+ - most effective against viral infections; induce apoptosis; MHC-1
Passive immunity
Transfer of anitbodies to an individual
Active immunity
the immune system is stimulated to produce antibodies against a specific pathogen
T-cells
Involved in cell-mediated immunity. They are the only specific defense against intracellular pathogens.
Four types:
- cytotoxic, helper, memory, supressor
