Musculoskeletal Flashcards
What is the brand name example of Tizanidine?
Zanaflex
What class of drugs does Tizanidine belong to?
Muscle relaxants
What conditions is Tizanidine commonly used to manage?
Muscle spasticity caused by conditions such as multiple sclerosis, spinal cord injuries, or other neurological disorders
How does Tizanidine work in the body?
It stimulates alpha-2 adrenergic receptors in the spinal cord, reducing the release of excitatory neurotransmitters and decreasing muscle tone
What is one off-label use of Tizanidine?
Back pain or muscle tension
What is the typical way Tizanidine is administered?
Orally as a tablet or capsule
What is a common starting dose of Tizanidine for patients?
2 mg every 6–8 hours
What should patients avoid regarding Tizanidine dosage?
Taking more than the prescribed dose
What is a common side effect of Tizanidine?
Drowsiness or fatigue
List three common side effects of Tizanidine.
- Drowsiness or fatigue
- Dizziness or lightheadedness
- Dry mouth
What precaution should be taken when using Tizanidine?
Avoid driving or operating heavy machinery until you know how it affects you
With which type of medications does Tizanidine interact significantly?
CYP1A2 inhibitors like ciprofloxacin or fluvoxamine
Who should use Tizanidine cautiously?
People with liver or kidney problems
Who should avoid using Tizanidine?
People with severe liver dysfunction
Fill in the blank: Tizanidine can cause significant _______.
drowsiness
