Muscular Tissues Part 2 Flashcards
outer layer, encircling the entire muscle
epimysium
surrounds groups of 10 to 100 or more muscle fibers, separating them into bundles called fascicles
perimysium
surrounds and separates individual muscle fibers from one another
endomysium
three kinds of proteins:
contractile proteins
regulatory proteins
structure proteins
generate force during contraction
contractile protein
help switch the contraction process on and off
regulatory proteins
keep thick and thin filaments of myofibrils in proper alignment, give myofibrils elasticity and extensibility, and link myofibrils to sarcolemma and extracellular matrix
structural proteins
two types of contractile proteins
myosin
actin
makes up thick filament; a molecule consists of a tail and two myosin heads, which bind to myosin-binding sites on actin molecules of thin filament during muscle contraction
myosin
these two both functions as a motor protein in all three types of muscle tissue
myosin and actin
main component of thin filament; each one of this molecule has a myosin-binding site where myosin head of thick filament binds during muscle contraction
actin
two types of regulatory proteins
tropomyosin
troponin
component of thin filament; when skeletal muscle fiber is relaxed, this covers myosin/binding sites in actin molecules, thereby preventing myosin from binding to actin
tropomyosin
makes up thick filament; molecule consists of a tail and two myosin heads, which bind to myosin-binding sites in actin molecules of thin filament during muscle contraction
troponin
five types of structural proteins
Titin
a-Actinin
Myomesin
Nebulin
Dystrophin
connects z disc to M line of sarcomere, thereby helping to stabilize thick filament position; can stretch and then spring back unharmed, and thus accounts for much of the elasticity and extensibility of myofibrils
titin
structural protein of z discs that attaches to actin molecules of thin filaments and to titin molecules
a-actinin
forms m line of sarcomere; binds to titin molecules and connects adjacent thick filaments to one another
myomesin
wraps around entire length of each thin filament; helps anchor thin filaments to z discs and regulates length of thin filaments during development
nebulin
links thin filaments of sarcomere to integral membrane proteins in sarcolemma, which are attached in turn to proteins in connective tissue matrix that surrounds muscle fibers; thought to help reinforce sarcolemma and help transmit tension generated by sarcomeres to tendons
dystrophin
skeletal muscle fibers are classified into three main types:
slow oxidative fibers
fast oxidative-glycolytic fibers
fast glycolytic fibers
two fibers that appear dark red bcs of large amounts of myoglobin and many blood capillaries
slow oxidative fiber
fast oxidative-glycolytic fiber