Muscular System and Muscle Tissue Flashcards
4 functions of the muscular system
- BODY MOVEMENT
- STABILIZATION of body position
- MOVEMENT OF MATERIALS through the body
- TEMPERATURE regulation (generates ~85% of body heat)
3 types of muscle tissue
- Skeletal muscle
- Cardiac muscle
- Smooth muscle
5 characteristics of all muscle cells
- Excitability
- Conductivity
- Contractility
- Extensibility
- Elasticity
Ability to respond to stimuli
Excitability
Characteristic of muscle cell that allows a nerve impulse to be carried deep into the cell
Conductivity
Ability to shorten
Contractility
Ability to lengthen
Extensibility
Ability to return to its original shape
Elasticity
Contracts to move the bones
Skeletal muscle
Contracts voluntarily
Skeletal muscle
Type of muscle tissue that contracts to beat the heart and begin the movement of blood
Cardiac muscle
Name for the muscle of the heart wall
Myocardium
Rate of contraction is altered by neural and hormonal control
Cardiac muscle
- Contracts to move food through the digestive system
- Lines arteries to keep blood moving
Smooth muscle
- Lines the walls of hollow organs
- Responds to nerve impulses as well as hormones and stretch
Smooth muscle
Highly vascularized connective tissue “wrappers” that hold muscle together or divide it into sections
Fasciae
Name of fascia that covers entire muscle
Epimysium
Name of fascia that covers fascicles
Perimysium
Name of fascia that covers individual muscle fibers
Endomysium
Connects muscle to bone
Tendon
A broad flat tendon
Aponeurosis
Name for muscle cells
Muscle fibers
Plasma membrane of a muscle fiber
Sarcolemma
Cytoplasm of a muscle fiber
Sarcoplasm
3 characteristics of sarcoplasm
- Contains glycogen
- Contains myoglobin
- Contains MANY mitochondria
Polysaccharide made up of a long chain of glucose molecules
Glycogen
Molecule that holds oxygen in the sarcoplasm
Myoglobin
Organelle that converts glucose into ATP
Mitochondria
Transverse Tubule (T-Tubule)
Allows nerve impulses to be carried deep into a muscle cell
Chemical reaction which breaks down glycogen into glucose
Hydrolysis
Smooth endoplasmic reticulum specialized for Calcium ion (Ca+2) storage and release
Sarcoplasmic reticulum (SR)
Made up of myofilaments arranged in sarcomeres
Myofibril
Many sarcomeres connected by Z-discs
Myofibril
Another name for thin myofilament
Actin myofilament
Another name for actin myofilament
Thin myofilament
Another name for thick myofilament
Myosin myofilament
Another name for myosin myofilament
Thick myofilament
Made up of:
- actin
- troponin
- and tropomyosin
Thin (actin) myofilament
Another name for the myosin-binding site of an actin molecule
Active site
Another name for the active site of an actin molecule
Myosin-binding site
Molecule which covers the active sites on actin when a muscle is at rest
Tropomyosin
- Protein attached to tropomyosin
- Has a “high affinity” for Ca ions (Ca+2)
Troponin
Molecules whose names end in “-ASE”
Enzymes
Composed of “golf club”-shaped myosin molecules
Myosin (thick) myofilaments
Enzyme contained in the “golf club” head of a myosin molecule
ATPase
Part of the myosin molecule that binds to an open actin active site during muscle contraction
Head
Enzyme that releases energy stored in ATP
ATPase
- Connects adjacent sarcomeres
- Thin myofilaments attach here
Z-disc
Area of overlap between thick and thin myofilaments
A band (anisotropic band)
- Center of A band
- Contains only thick myofilaments
H zone
Band composed of only thin myofilaments
I band (isotropic band)
Formed by the binding of a myosin head to an active site
Cross-Bridge
Name for the movement of a thin filament past a thick filament
Power stroke
Area where nerve and muscle are in close proximity
Neuromuscular junction (NMJ)
Synapse between motor neuron and muscle
Neuromuscular junction (NMJ)
Name for a nerve cell
Neuron
The bulbous end of a neuron
Presynaptic terminal
- Membrane-bound bubbles in the presynaptic terminal
- Contain ACh
Synaptic vesicles
Neurotransmitter needed to begin muscle contraction
Acetylcholine (ACh)
Physical space between neuron and muscle cell
Synaptic cleft
- Enzyme that breaks down ACh
- Found in the synaptic cleft
Acetylcholinesterase (AChE)
- Inability for muscle to relax
- Side effect of death
Rigor mortis
When rigor mortis begins
~3-4 hours after death
When rigor mortis peaks
~12 hours after death
When rigor mortis dissipates
~48-60 hours after death
All or None Principle
If a nerve impulse is strong enough to cause a contraction then the muscle fibers contract maximally (all the way); otherwise they don’t contract at all
Produced by the many mitochondria found in the sarcoplasm
Adenosine Triphosphate (ATP)
Ultimate goal of cellular respiration
To break down glucose COMPLETELY into: CO2, H20, and energy (ATP)
C6H12O6
Glucose
3 steps to completely breakdown glucose (cellular respiration)
- Glycolysis
- Citric Acid Cycle (Kreb’s Cycle)
- Electron Transport System (ETS)
Aerobic conditions
“In the presence of oxygen”
- 1st step of cellular respiration
- Takes place in the cytosol
- Does NOT require oxygen
- Chemically splits glucose in half to form 2 molecules of pyruvic acid
Glycolysis
Amount of ATP released by one glycolysis reaction
2
C3H6O3
Pyruvic acid
Folds of the inner membrane of the mitochondria
Cristae
Spaces between the folds of the cristae of a mitochondria
Matrix
- 2nd step of cellular respiration; Requires oxygen
- Takes place in the matrix of the mitochondria
- Uses pyruvic acid to form 4 CO2 + 2 ATP + molecules needed for ETS
Citric Acid Cycle (Kreb’s Cycle)
Products of the citric acid cycle (Kreb’s cycle)
- 4 CO2
- 2 ATP
- molecules needed for Electron Transport System (ETS)
Group of muscle cells wrapped up in perimysium
Fascicle
- 3rd step of cellular respiration
- Requires oxygen
- Reactions take place in the cristae of the mitochondria
- Produces 34 ATP, 2 CO2, and 6 H2O
Electron Transport System (ETS)
- Builds up in muscles and causes cramps
- Created out of pyruvic acid (under anaerobic conditions)
- Can be converted into glucose by the liver
Lactic acid
After exercise, extra oxygen is needed to break down lactic acid. This debt is “repaid” by heavy breathing.
Oxygen debt
- Inability of a muscle to maintain its strength of contraction
- Caused by extensive muscle use
- Related to insufficient oxygen, depletion of glycogen, and a build up of lactic acid which decreases the pH of cells
Muscle fatigue
- Muscle shortens and pulls on another structure (e.g. bone)
- Produces movement
- Tension is constant
- Energy is used
Isotonic muscle contraction
- Minimal shortening of muscle
- Tension increases greatly
- No body movement
- Energy is still used
Isometric muscle contraction
A condition where individual muscle fibers decrease in size due to a loss of myofibrils
Muscular atrophy
Muscular atrophy due to lack of use
Disuse atrophy
- Caused by nerve supply to a muscle being cut
- Myofibrils become replaced by fibrous tissue
Denervation
- Increase in the SIZE of muscle fibers
- Due to an increase in the number of myofibrils
Muscular hypertrophy
- Muscle cells lack striations
- Contain thick, thin, and intermediate myofilaments which are NOT arranged in a regular pattern
Smooth muscle
Stretched between the dense bodies in a smooth muscle cell
Intermediate myofilaments
Products of aerobic cellular respiration
- 38 ATP
- 6 CO2
- 6 H20