Muscular (E3) Flashcards
3 layers of skeletal muscle
- Epimysium
- Perimysium
- Endomysium
Components of myofibrils
Sarcomere composed of thin and thick filaments and Z & M lines or discs
Thick filaments
Composed mainly of myosin which is made up of 2 heavy chains and 4 light chains
Thin filaments
Composed of actin, nebulin, troponin, and tropomyosin
Muscle tone
Resistance to stretch exhibited by a relaxed muscle
- due to baseline calcium in the cytosol
Intrinsic muscle tone in smooth muscle
Due to baseline Ca+ levels in the cytosol causing low level tension activity
Alpha motor neurons
-innervate skeletal muscle fibers
-cell bodies are located in the brainstem and spinal cord
T/F: all neuromuscular junctions are excitatory.
True
Botulinum toxin
Neurotoxin released from clostridium botulinum
-blocks Ach release
Curare
-blocks Ach receptors
-similar in action to nondepolarizers
T/F: a muscle cell has multiple nuclei
True
Satellite cells
Undifferentiated stem cells that repair damaged or destroyed skeletal muscle fibers
Skeletal muscle
-attached to bones by tendons
Sarcomere
One unit of thin and thick filaments
Wide dark bands in the middle
A band