Muscular drugs Flashcards

1
Q

what does acetylcholinesterase do?

A

breaks down acetylcholine

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2
Q

myopathies

A

disorders of muscles

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3
Q

neuromuscular blockers function

A

produce paralysis by disrupting the transmission of nerve impulses

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4
Q

skeletal muscle spasmolytics function

A

reduce muscle spasms

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5
Q

inflammation

A

normal response of living tissue to injury, infection, or irritation, involves vascular changes and release of chemicals that help the body destroy harmful agents at the injury site

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6
Q

what are the two types of anti-inflammatory drugs?

A

steroidal and nonsteroidal

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7
Q

what do neuromuscular blockers cause?

A

no analgesia (ability to feel pain), no sedation, need to give positive pressure ventilation

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8
Q

competitive non-depolarizers

A

drugs that block activity at the neuromuscular junction, inhibit effects of ACh

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9
Q

what is a common adverse effect among competitive non-depolarizers?

A

increased blood pressure/ heart rate

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10
Q

antidotes

A

substances given to counteract the effects of another drug

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11
Q

what drugs are antidotes?

A

neostigmine, pyridostigmine, edrophonium

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12
Q

how do antidotes work?

A

bring more ACh into muscle site, reverse the paralyzing effects of competitive non-depolarizers

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13
Q

depolarizing drug

A

muscle paralyzing drugs that depolarize the cell membrane of muscle fibers by mimicking the action of ACh

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14
Q

what is an example of a depolarizing drug?

A

Succinylcholine

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15
Q

what drug doesn’t need an antidote because of how fast it works?

A

Succinylcholine

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16
Q

spasmolytics

A

drug used to treat acute episodes of muscle spasticity associated with neurological and musculoskeletal disorders

17
Q

what does spasmolytics treat?

A

malignant hyperthermia, equine post anesthetic myositis, traumatic injury that results in muscle spasms

18
Q

what drugs are classified as spasmolytics?

A

Methocarbamol (treats inflammatory and traumatic conditions), Guaifenesin (muscle relaxant), Diazepam (centrally acting muscle relaxant), dantrolene (peripherally acting muscle relaxant)