Muscular drugs Flashcards
what does acetylcholinesterase do?
breaks down acetylcholine
myopathies
disorders of muscles
neuromuscular blockers function
produce paralysis by disrupting the transmission of nerve impulses
skeletal muscle spasmolytics function
reduce muscle spasms
inflammation
normal response of living tissue to injury, infection, or irritation, involves vascular changes and release of chemicals that help the body destroy harmful agents at the injury site
what are the two types of anti-inflammatory drugs?
steroidal and nonsteroidal
what do neuromuscular blockers cause?
no analgesia (ability to feel pain), no sedation, need to give positive pressure ventilation
competitive non-depolarizers
drugs that block activity at the neuromuscular junction, inhibit effects of ACh
what is a common adverse effect among competitive non-depolarizers?
increased blood pressure/ heart rate
antidotes
substances given to counteract the effects of another drug
what drugs are antidotes?
neostigmine, pyridostigmine, edrophonium
how do antidotes work?
bring more ACh into muscle site, reverse the paralyzing effects of competitive non-depolarizers
depolarizing drug
muscle paralyzing drugs that depolarize the cell membrane of muscle fibers by mimicking the action of ACh
what is an example of a depolarizing drug?
Succinylcholine
what drug doesn’t need an antidote because of how fast it works?
Succinylcholine