Muscular Contraction Flashcards
Three types of contraction
isometric, eccentric, concentric
Passive contraction
contraction of titin within muscles, like spring action to maintain proper overlapping of actin and myosin filaments
Active force
the force of the filaments sliding past each other during the power stroke (main power of muscle)
Total force
Sum of active and passive forces
Clinical detection of muscle tear
elevated creatinine levels in the serum
Duchenne disorder characterization
mutation in dystrophin; x-linked recessive
Duchenne Pathophys
lack of dystrophin causes the glycoprotein matrix that supports the sarcomeres’ connection to the muscle membranes to be susceptible to degradation
Amount of twitches done by stored ATP
8
ATP in muscles used by
Na/K ATPase; Ca SR pump (ATP powered); actomyosin ATP-ase
ATP replenishment
Creatine phosphate and ADP combine via action of creatine kinase to form ATP
Energy use (order)
Actomyosin ATP-ase
S.R. Ca pump
Other metabolic functions
fast twitch
glycogen containing (FG); appear white type IIb
Slow twitch
many mitochondria = lots of myoglobin
slow/oxidative (SO) type I
FOG
fast twitch with mitochondria and oxidative phospho. type IIa