Definitions Flashcards
Partition Coefficient
Hydrophobicity
Crenation
formation of spines on RBC’s due to hyperosmotic solution
RBC Ghost
remnants of an RBC that lysed (hemolysis)
Spherocytosis
RBC’s that are prone to lysis caused by mechanical deformation - lyse at 90 mosmol/L NaCl instead of 70 mosmol/L NaCl
Oncotic pressure
osmotic pressure brought about due to charged ions attracting water electrically
Alternating Access Model
Description of carrier transport; specifically that it can only transport only when activated sites are available, and then a conformation change can take place. An “open-shut-open” model
Uniport
Moves only one type of substrate, usually called facilitated diffusion
Secondary Active Transport
Using the gradient of one molecule to push another molecule against its gradient. Can be symporters or antiporters
Active Transport
Direct energy investment to move molecules against their gradient
P Type Pump
Uses ATP hydrolysis on the cytoplasmic side to pump ions across the membrane
Na/K-ATPase is an example
P-Type Pump E1
Cytoplasmic side binding site open
P-Type Pump E2
Extra-cellular side binding site open
V-Type Pump
Uses ATP hydrolysis to pump protons against their gradient; just like ATP synthase only in reverse
Examples of V-Type Pump
Kidney pumping protons into the urine
Osteoclast pumping protons onto bone
Sperm pump protons into the acrosome
Types of Uniporters
Glucose, Urea, Some Amino Acids, Fatty Acids
