Muscles Flashcards
3 types of muscle
Smooth (involuntary)
Striated/skeletal (voluntary)
Myocardium (cardiac muscle)
Neuromuscular junction
Where the nerves reach the motor end plate - nerve endings
Striated muscle structure
Muscles are made of muscle fibres
Each fibre is made up of myofibrils
Each functional unit of a muscle is a sarcomere
2 contractile proteins
Myosin (with myosin heads) and actin (chains of proteins)
Structure: myosin is strung between 2 actin filaments
Tropomyosin
Inhibitory protein which holds the troponin complex
Troponin complex is made up of…
Troponin I (inhibitory) Troponin C (calcium binding site) Troponin T (tail)
Muscle contraction
- Nerve impulse causes cell to depolarise
- Sodium channels open -> further depolarisation
- Calcium channels are opened, calcium enters cell
- Calcium binds to receptor on sarcoplasmic reticulum
- Massive store of calcium is liberated
- Calcium binds to troponin C
- Troponin complex moves, allowing myosin head to bind to actin
ATP and relaxation
ATP stops the interaction between actin and myosin
Also actively pumps ions to normalise intracellular concentrations between contractions
Tendons
Connect muscle to bone - strong, fibrous tissues
Proprioception
Awareness of your physical self allowing conscious and subconscious coordination of the body.
Muscle spindles/proprioceptor in muscle constantly measures stretch
Cerebellum feeds into spinal cord input (feedback from eyes)
Vestibular organs feed into spinal cord input (fluid-filled semi-circular canals in the ear, with hairs to detect fluid movements across x, y and z dimensions)