Cell Biology Flashcards
Homeostasis is…
Involuntary neuronal and hormonal control of the body environment to keep all physical parameters within normal limits
Total body water =
0.6 x body weight
Extracellular water is … of total body water
1/3
3/4 interstial and 1/4 plasma
Which ion is higher in intracellular fluid?
Potassium
Diffusion
Solute movement from a higher concentration to a lower concentration
Osmotic pressure
Concentration gradient caused by unequal distribution of ions across a semi-permeable membrane causing water to move towards the high electrolyte concentration
Keeps water in the blood vessel
Oncotic pressure
Concentration gradient caused by unequal distribution of macro-molecules across a membrane
Keeps water in the blood vessel
Which pressure is greater? Why?
Oncotic pressure is greater than osmotic pressure as proteins are much larger than water and have a greater water pull than ions
Why is water attracted to ions?
When water is formed, oxygen pulls electrons from hydrogen ions, creating a positive pole and a negative pole.
1 molecule of water will bind 1 sodium or potassium ion.
= dissolving.
Hydrostatic pressure
Pushes water out of the blood vessel
Blood pressure in the capillary
- Hydrostatic pressure from arties is high - forces fluid out
- Hydrostatic pressure drops over length of capillary
- By the time blood reaches veins, hydrostatic pressure is lower than oncotic pressure, so fluid is reabsorbed into blood
Factors causing extravasation (fluid movement out of blood vessel) (4)
Increased BP
Blocked Lymph drainage
Inflammation
Liver failure
Factors causing fluid retention (2)
Hypernatremia (too much sodium)
Renal failure
Chemical communication in the body
- Stimulus
- First messenger (hormone or neurotransmitter)
- Receptor
- Secondary messenger (change how cell responds)
- Inhibitory or excitatory action
- Cellular response
Negative feedback
Most common form of feedback
Normally, neurotransmitter is released from nerve ending and binds to target
Negative feedback is when neurotransmitter binds to pre-synaptic nerve, inhibiting more neurotransmitter release