Muscles Flashcards

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1
Q

sarcolemma

A

cytosol of a muscle cell

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2
Q

sacroplasm

A

cytoplasm of a muscle cell

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3
Q

sarcomere

A

gives striation to the muscle cell
made up of thick and thin filaments
fundamental to muscle contraction

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4
Q

motor unit

A

= 1 motor neuron + all the muscle fibers the neuron innervates
those with fewer muscle fibers are better for precise movement

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5
Q

characteristics of muscle fibers

A

excitability
contractibility
extendability
elasticity

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6
Q

parts of a sarcomere

A
A-band 
I-band 
H-zone 
M-line
Z-line
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7
Q

A-band

A

myosin filaments

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8
Q

I-band

A

actin filaments and Z-line

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9
Q

H-zone

A

area of myosin that DOESN’T overlap

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10
Q

M-line

A

middle of myosin filament

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11
Q

Z-line

A

anchored actin filament

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12
Q

what changes in the sarcomere when a muscle contracts?

A

z-lines move closer together
I-band shortens
H-zone disappears

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13
Q

what are thin filaments mostly made of?

A

actin filaments

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14
Q

what are thick filaments mostly made of?

A

myosin

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15
Q

anatomy of myosin

A

head: binds actin

neck and tail: have variable lengths

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16
Q

which myosin type is present in muscles?

A

myosin II

17
Q

myosin II

A

aka muscle myosin

has very long tail region that gives the structure of thick filaments

18
Q

myosin I

A

acts as an anchor between the cell membrane and the cytoskeleton

19
Q

myosin V

A

transports various cargo molecules

one of the main transport molecules

20
Q

proteins involved in regulating access to myosin binding sites

A

troponin

tropomyosin

21
Q

tropomyosin

A

binds and obscures myosin binding sites

22
Q

troponin

A

respond to calcium ions

23
Q

troponin subunits

A

TnC: binds to calcium ions
TnI: interacts with actin and obscures the binding site
TnT: interacts with tropomyosin

24
Q

proteins responsible for changes in intracellular calcium ion concentration

A
ATPase 
SERCA
sodium/calcium reversible exchanger
L-type calcium channel
RyR
25
Q

ATPase

A

actively transports calcium ions outside the cell

26
Q

SERCA

A

actively transports calcium ions from the sarcoplasm into the sarcoplasmic reticulum (SR)

27
Q

sodium/calcium reversible exchanger

A

moves sodium and calcium either inside or outside the cell

28
Q

L-type calcium channel

A

first responder to voltage changes across the sarcolemma

29
Q

RyR

A

calcium channel that allows calcium to rapidly exit the SR

is where most of the intracellular calcium comes from

30
Q

factors that determine the force of muscle action

A

the length of the muscle fiber before stimulation
the number of recruited motor units
the frequency of neuronal stimulation

31
Q

summation

A

stimuli of increasing frequency that result in combining individual twitches

32
Q

which type of muscle is NOT striated?

A

smooth (visceral) muscle

33
Q

fast twitch muscle

A

reaches depolarization faster because of the number and the properties of the present sodium and calcium channels

34
Q

slow twitch muscle

A

has slower depolarization and a longer contraction cycle

35
Q

cardiac muscle

A

contraction is similar to slow twitch muscles, but differs in repolarization

36
Q

what stimulates contraction of cardiac muscle?

A

pacemaker cells

37
Q

what forms connections between the cytoplasms of two cardiac muscle cells?

A

desmosomes

gap junctions

38
Q

which type of muscle has NO organized sarcomeres?

A

smooth (visceral muscle)