Muscles Flashcards
A single skeletal muscle is called____.
Muscle fiber
Each muscle fiber is formed during development by the fusion of a number of undifferentiated mononucleated cells, known as ____
Myoblasts
Definition of a muscle?
is a number of muscle fibers bound together by connective tissue (collagen)
Muscles are connected to bones by ____.
Tendons (which are made by collagen)
What is the relationship between a motor neuron and muscle fibers?
one motor neuron innervates around 100 muscle fibers
Definition of a motor unit?
motor neuron and muscle fibers it controls (usually around several hundred)
A disease that involves the progressive degeneration of lower motor neurons
Spinal Muscular Atrophy
Disease that causes nonprogressive degeneration of upper motor neurons in one cerebral hemisphere:
Stroke
Disease that causes the progressive degeneration of neurons in Substantia Nigra
Parkinson’s Disease
Synchronous firing of all upper motor neurons
Seizure (epilepsy)
Disease that causes progressive degeneration of upper and lower motor neurons in both cerebral hemispheres:
Amyotrophic lateral sclerosis (ALS)
Progressive degeneration of myelin in central nervous system
Multiple Sclerosis (MS)
The strength of muscle contraction depends on:
1) The number of motor units recruited
2) The frequency of a motor unit discharge
3) The speed of contraction of muscle fibers in the motor unit
4) The nature of a motor unit (whether it is fatigue-resistant or fatigue-prone)
Stack many sarcomeres together longitudinally and you have a _____.
Myofibril
Name the protein that covers myosin binding sites on actin
Tropomyosin