Muscles Flashcards

1
Q

A single skeletal muscle is called____.

A

Muscle fiber

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2
Q

Each muscle fiber is formed during development by the fusion of a number of undifferentiated mononucleated cells, known as ____

A

Myoblasts

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3
Q

Definition of a muscle?

A

is a number of muscle fibers bound together by connective tissue (collagen)

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4
Q

Muscles are connected to bones by ____.

A

Tendons (which are made by collagen)

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5
Q

What is the relationship between a motor neuron and muscle fibers?

A

one motor neuron innervates around 100 muscle fibers

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6
Q

Definition of a motor unit?

A

motor neuron and muscle fibers it controls (usually around several hundred)

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7
Q

A disease that involves the progressive degeneration of lower motor neurons

A

Spinal Muscular Atrophy

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8
Q

Disease that causes nonprogressive degeneration of upper motor neurons in one cerebral hemisphere:

A

Stroke

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9
Q

Disease that causes the progressive degeneration of neurons in Substantia Nigra

A

Parkinson’s Disease

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10
Q

Synchronous firing of all upper motor neurons

A

Seizure (epilepsy)

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11
Q

Disease that causes progressive degeneration of upper and lower motor neurons in both cerebral hemispheres:

A

Amyotrophic lateral sclerosis (ALS)

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12
Q

Progressive degeneration of myelin in central nervous system

A

Multiple Sclerosis (MS)

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13
Q

The strength of muscle contraction depends on:

A

1) The number of motor units recruited
2) The frequency of a motor unit discharge
3) The speed of contraction of muscle fibers in the motor unit
4) The nature of a motor unit (whether it is fatigue-resistant or fatigue-prone)

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14
Q

Stack many sarcomeres together longitudinally and you have a _____.

A

Myofibril

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15
Q

Name the protein that covers myosin binding sites on actin

A

Tropomyosin

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16
Q

Name Ca2+ sensitive protein that controls cross bridge cycle

A

Troponin

17
Q

What does troponin do once it is bound to calcium?

A

It swings tropomyosin away from the rails (actin) from its locomotive (myosin), thus exposing the myosin binding site, allowing a cross bridge to form, and a muscle to contract

18
Q

What keeps muscle from continuous contractile activity?

A

Tropomyosin is held by Troponin in resting muscle in the position that does not allow myosin to bind to actin

19
Q

Where does calcium come from in a neuron?

A

Extracellular fluid (EF)

20
Q

Name the muscle length sensors

A

Muscle spindle

21
Q

Name the muscle tension sensors

A

Golgi tendon organ