Muscle Physiology I Flashcards
Exam 1
What are the characteristics of muscle tissue?
- irritabilility/exciltability: able to receive and respond to chemical, electrical, and mechanical stimulus
- contractilicity: muscles change shape as a result of stimuli becoming shotere and thicker, and develops tension.
- relaxation: the opposite of contractibility: the giving up of tension
- extensibility: muscle can be stretched or lengthened by a force outside of the muscle itself
- elasticity: muscle tissue readily returns to normal length when a stretching force is eliminated
What is the purpose of skeletal muscles
- generate movement
- arrest movement
- modify movement
Muscles actively exert force by shortening and building up tension or passively exeriting force by resisting stretch
What are rotary and translatory movements
- rotary: plane that moves around an axis, (ex: add/abduction)
- translatory: moves around the whole body not just a joint
What is the structure of a skeletal muscle?
- endomesium: coating around a muscle fiber (like plastic wrap), seperates one muscle fiber from the other
- fasicle: group of endomesium bundled wiyh perimesium
- perimysium: sheath that surround the muscle fasicles (bundles). [in long muscles it may be arranged chain-like and extends the length of the muscle]
- epimysium: tough outermost layer, surrounds the entire muscle tissue/belly. Helps give muscle its shape and is very resistant to stretch (think of a corset)
- tendon: receives contributions from all connective tissue layers, it develops tension when the muscle shortens or is on stretch
- periosteum: highly vascularized CT that is the outer layer of the bone; tendons and ligaments be;lnds into it. It provides nourishment
What is actin?
thin, light, 2 chain-like strings of actin molecules are wound around each other. They form the I band of the sarcomere
What is myosin?
The thick, dark, large molecules. Has globular head groups that swivel and attch to binding sites on actin (crossbridge). The “H” zone is central protion of the myosin filament
Describe the A band, I band, & H zone, and M band
- A-band: overlapp of myosin and actin fillaments
- I-band: thin actin
- H zone: only myosin; this is the contractile region, no overlapping
- M band: the part of the h-zone that contains myosin filaments that connect to one myosin filament
Important details about actin-myosin crossbridging
- during the shortening of the muscle, the actin is pulled towards the myosin–crossbridges are formed, broken, and reformed as greater overlapp occurs
- During lengthening contractions, the actin pulls away from the myosin–crossbridges are broken, reformed, and broken as graduak reduction in overlapp occurs
- The degree of overlapp is the only thing that changes, the actin/mysoin dont actually change in length
What are the functions of connective tissue?
- bind muscles together
- harnesses the force of muscle contraction and transmits this force to the bony attachmnets via the tendons
- provides structure and shape
- a conduit for blood vessels and nerves
- contributes to passive tension to the muscle fiber as the muscle contracts or stretches
What are the passive contributors to muscle tension?
- various tissues, just by being there, contributes **passive tension **
What are the passive elastic components?
CT is associated with muscle tissue: endomysium, perimysium, epimysium, tendon; they are all interconnected
* they contribute to overall tension present in a muscle, Lengtyen or shorten when the muscle actively does these
What are the non-connective tissue elastic components
- the sarcolema, nerve, and blood vessels will also contribute to tension to the overall muscle contraction by lengething and shortening as the muscle contracts and relaxes
What is the difference between fusiform and penniform fibers of muscles?
- Fusiform: arranged in elongatyed/parallel fashion. Provide greatest degree of shortening, = quick muscle and good ROM
- Penniform: shorter fibers, oblique arrangement, = greater force but smaller ROM
Describe crossbridge formation?
Crossbridge formation occurs when a muscle is stimulated at its motor end plate and a chemical change occurs in the sarcomere.
- an influx of Ca+ triggers the exposure of binding sites on actin
- then head groups of the myosin swivel causing the actin to be pulled along the length of the myosin (this is called “power stroking”
- As the actin slides past the myosin, a chemical reaction occurs which binds the actin to the myosin
- As crossbridges form and old ones are rebuilt, the actin is moved closer to the H zone of the sacromere, until a maximum overlap occurs (no more increase in tension can develop in the fibers)
- The fillaments do not change in length, however the sacromere (contracile unit) becomes shorter
What is the sarcolemma, myofibril, sarcomeres, and Z-lines?
- Sarcolemma: singe muscle cell surrounded by a cell membrane
- Myofibril: threadlike structure runs through the muscle cell and allows the muscle to contract
- Sacromeres: a series of units that makes up the myofibril, and extends between two Z-lines
- Z-lines: located at regular intervals throughout the myofibril and act as boundaries for the sarcomere and a means of linking the actin fillaments together
What are red (tonic fibers)?
- Type I, slow oxidative, slow twitch
- innervated by lower thresholds than pale fibers, so used more frequently
- fibers designed for endurance
- red, small diameter, high myogliobin (oxidative) capacity, small MU size and slow axon conduction
What are pale (phasic fibers)?
- Type IIa/b, fast twitch, glycolic
- for rapid contractions, less capable of sustained contractions
- innervated by higher thresholds than red fibers
- desinged for short term bursts of energy
- white, large diameter, low myoglobin contenet (oxidative capacity), high glyocolic capacity, fast fatigue, large MU size and fast axon conduction
What is the muscle fiber’s response to a single brief stimulus?
a muscle twitch
- the muscle contracts quickly and relaxes
What are the 3 types of sensory neurons?
- exteroceptors: conduct electrical impulses of sensation from outside the body (touch, smell, vision)
- Proprioceptors: located in muscles, tendons, and ear that bring info about postion in space (pressure, movement, equilibrium)
- Interoreceptors: located deep in viscera and detect stimuli from internal organs and blood vessels
What is a motor unit?
fibers of skeletal muscles that are organized into motor units, they vary in size. On average, there are 150 fibers in each motor unit
- motor unit: the motor nerve fiber and all the muscle fibers it serves/innervates (via the axon)
- motor units are not grouped together but are dispersed throughout the muscle
- the more motor units stimulated, the greater the contraction