Muscle Damage Flashcards
1
Q
What are the suggested causes of muscle damage from exercise
A
- mechanical disruption of sarcomeres
- structural or metabolic alterations influenced by higher local muscle temp
- impaired mitochondrial respiration
- increased free radical production
2
Q
What types of structural damages are seen in damaged muscle
A
- sarcolemma disruption
- changes in extracellular myofibre matrix
- distortion of myofibrillar components
- lesions of plasma membrane
- swollen mitochondria
- fragmented sarco rec
- damage to cytoskeleton
- dilated T tubules
3
Q
Objective symptoms of muscle damage
A
- increased plasma enzymes (creatine) (slow effect)
- increased myoglobin
- increased protein metabolites
- structural damage to fibres
