Muscle Flashcards

1
Q

What happens when muscle is injured (necrosis & regeneration)?

A
  1. damage => microfibre necrosis
  2. Inflammation & phagocytosis
  3. Hypercontration of myofibrils (> stop necrosis/cell death from spreading to rest of cell)
  4. revascularisation
  5. Satellite cells activate & proliferate
  6. fusion of myoblast & myotubules
  7. re-innercation
  8. growth & maturation
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2
Q

What are satellite cells and their function?

A

muscle-specific stem cells
> facilitate post-natal growth & regeneration:
- activate, proliferate, differentiate & fuse into yofibres

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