Muscle Flashcards
Three types of muscle
skeletal, smooth, and cardiac
Skeletal Muscle
Striated Voluntary (somatic nervous system) Many nuclei per cell
Slow Twitch
AKA Red Fibers High myoglobin content Primarily derive energy aerobically Contain many mitochondria
Fast twitch
AKA white fibers Less myoglobin (rely on glycolysis and fermentation to make ATP)
Smooth Muscle
Involuntary action (autonomic nervous system) Single nucleus in cell Capable of tonus Myogenic activity
Myogenic activity
Can contract without nervous system input`
tonus
a constant state of low-level contraction -may be seen in blood vessels
Cardiac muscle
Mainly uninucleated Involuntary (automatic nervous system) Striated Myogenic activity Depolarization: SA node–>AV node –>bundle of His–>Purkinje fibers
Sarcomere
Thick (myosin) and thin (actin) filaments Z-lines: end of the alphabet and the end of the sarcomere M-line: middle of the myosin filament I-band: I is a thin letter (thin filaments only) H-zone: H is a thick letter (thick filaments only) A-band: All of the thick filament (whether or not its overlapping) During contraction, all smaller except A band
Titin
a protein that acts as a spring and anchors the actin and myosin filaments together, preventing excessive stretching of the muscle
Myocyte
AKA muscle fiber Contains many myofibrils arranged in parallel. Many myocytes in parallel form a muscle
Sarcolemma
Cell membrane of a myocyte. Capable of propagating an action potential and can distribute to all sarcomeres using a system of transverse tubules.
Motor unit
The nerve terminal (end of neuron) and the group of myocytes it controls
Muscle contraction
Binding of ATP is required for releasing the myosin head from the actin filament.
Tropomyosin and Troponin
Proteins associated with actin microfilament. When action potential reaches sarcoplasmic reticulum, Ca is released–>binds to troponin–> conformational change in tropomyosin–>exposes myosin binding sites on actin