Muscle Flashcards

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1
Q

Muscle

A

Highly specialized tissue with ability to contract in response to stimuli

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2
Q

What three types of muscles do vertebrates have?

A

skeletal, cardiac, smooth

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3
Q

what is the organization of the muscle?

A

muscle–> muscle fiber–> myofibril

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4
Q

sarcomere

A

The basic unit of contraction. gives muscle a striated appearance.

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5
Q

Myosin contains what two kinds of filaments?

A

1.Thick filaments;
– Composed primarily of myosin;
2. Thin filaments;
– Composed of two chains of globular actin, wrapped around each other in a helix;

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6
Q

Titin

A

Structural elastic protein that align actin and myosin;an accessory protein for contraction.

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7
Q

What do tropomyosin and troponin do>

A

Associated with the actin chains of the thin filaments;

– Regulate contraction by controlling the interaction of the cross bridges with the thin filaments.

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8
Q

What happens during a muscle contraction?

A

the muscle fibbers contract, the thin and thick filament slide over each other.

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9
Q

what are the signals for a muscle contraction?

A

Motor neurons from the somatic NS generate action potentials that liberates ACh

ACh is secreted into the neuromuscular junction and binds to nicotinic receptors in the muscle cell membrane

Ca2+ is liberated from the sarcoplasmic reticulum


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10
Q

what does myosin ATPase catalyze?

A

the decomposition of ATP into ADP

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11
Q

In the absence of calcium what does tropomyosin do?

A

tropomyosin cover myosin-binding sites;

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12
Q

The binding of Myosin to actin create the formation of what?

A

crossbridge

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13
Q

where is calcium taken once the action potentials stop after muscle contraction?

A

sarcoplasmic reticulum.

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14
Q

What are the 3 types of muscle fibbers?

A

– Slow oxidative fibres; – Fast oxidative fibres; – Fast glycolitic fibres.

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15
Q

oxidative fibers

A

Contain large number of mitochondria:
– High capacity for oxidative phosphorylation:
– Surrounded by many small blood vessels;

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16
Q

What colour of meat is oxidative fibbers?

A

Red meat. i.e breast of a duck

17
Q

glycolytic fibers

A

Few mitochondria but high concentration of glycolytic enzymes and large stores of glycogen;
– Limited use of oxygen;
– Few blood vessels
– Little myoglobin,

18
Q

What are the 3 major types of muscle fibers>

A
  1. slow oxidative fibers
  2. fast oxidative fibers
  3. fast glycolytic fibers
19
Q

slow oxidative fibers

A

Have low rates of myosin ATPase activity but have the ability to make large amounts of ATP
– Do not fatigue easily;
– Used for prolonged, regular activity;
• flight, long-distance swimming;

20
Q

Fast oxidative fibers

A

Fast-oxidative fibres:
– Have high myosin ATPase activity and can make large amounts of ATP;
– Do not fatigue quickly and can be used for long-term activities;
– They are particularly suited for rapid actions;

21
Q

fast glycolytic fibers

A

High myosin ATPase activity but cannot make as much ATP as oxidative fibres, because their source of ATP is glycolysis;
• Best suited for rapid, intense actions;
– Short sprint at maximum speed or a cat
pouncing on its prey;
• Fatigue more rapidly than oxidative fibres;

22
Q

Aerobic exercise of low intensity but long duration, increase what?

A

the number of mitochondria in the slow-oxidative fibres;

23
Q

High-intensity exercise of short-duration affects what?

A

fast-glycolytic fibres, which are used during strong contractions:

24
Q

What type of muscles are striated muscles?

A

Skeletal muscle and cardiac muscle

25
Q

What type of muscles are unstriated muscles?

A

Smooth muscle

26
Q

Striated muscle are

A

muscle tissue that has repeating sarcromeres in contract with smooth muscle tissue.

27
Q

The basic unit of contraction is termed the

A

Sarcomere

28
Q

Tendons:

A

Connective tissue that link bone to skeletal muscles

29
Q

What are the 2 roles of ATP:

A
  1. Binding ATP to myosin decreases affinity for actin.

2. Following dissociation ATP is hydrolyzed energizing myosin.