metabolism Flashcards

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1
Q

what is hypoglycaemia?

A

an inadequate supply of glucose to the brain

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2
Q

What are the negative effects of hypoglycaemia?

A

Effects can range from mild dysphoria, seizures, unconsciousness, permanent brain damage or death;

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3
Q

What is Hyperglycemia

A

Excessively high blood glucose

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4
Q

What are the negative effects of hyperglycaemia?

A

leads to cell dehydration. can cause cataract in the eyes.

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5
Q

Does Glycogen affect osmotic pressure?

A

NO!

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6
Q

where is glycogen found?

A

Glial cells and Liver

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7
Q

What is gluconeogenesis?

A

The production of glucose from a non sugar source.

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8
Q

glycogenolysis

A

breakdown of glycogen to produce glucose

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9
Q

Muscle glycogen is used for what?

A

internal use. (muscles)

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10
Q

Fatty acids cannot be made into glycogen, but what can?

A

glycerol. backbone of fatty acid

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11
Q

What does the adrenal medulla secrete

A

epinephrine

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12
Q

what does the adrenal cortex secrete?

A

glucocorticoids cortisol/corticosterone

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13
Q

What does the pituitary secrete?

A

GH

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14
Q

What does the thyroid gland secrete?

A

• T3 &T4

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15
Q

In the pancreas there is Islets of Langerhans are scattered in great numbers throughout. What doe the alpha and beta cells release>

A

alpha cells-glucagon

beta-insulin

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16
Q

when is insulin released?

A

when blood glucose is high

17
Q

When is glucagon released?

A

when blood glucose is low

18
Q

What are acute side effects of prolonged high blood sugar

A

High blood sugar include frequent urination, increased thirst, and increased hunger;
– Acute complications include diabetic ketoacidosis and nonketotic hyperosmolar coma;

19
Q

What are severe side effects of prolonged high blood sugar(diabetes mellitus)

A

Long-term complications include cardiovascular disease, stroke, chronic kidney failure, foot ulcers, and damage to the eyes

20
Q

What are the 3 types of diabetes?

A

Type 1 - pancreas fail to produce enough insulin;
Type 2 - insulin resistance;
– Cells fail to respond to insulin;
Gestational diabetes - pregnant women without a previous history of diabetes develop a high blood-sugar level.

21
Q

Diabetes is disease of the ______ system in which _____ is deficient or cells become resistant to it.

A

endocrine, insulin

22
Q

When insulin is released what does it increase?

A
  1. production of glycogen
  2. lipid synthesis
  3. esterfication of fatty acids
  4. amino acid uptake
23
Q

When insulin is released what does it decrease>

A
  1. proteolysis
  2. lypolysis
  3. gluconeogensis
24
Q

Cholesterol is a presursor for what 6 other hormones?

A
  • estradiol
  • cortisol
  • aldesterone
  • testosterone
  • progesterone
  • pregegonal
25
Q

what corticoids does the adrenal cortex release?

A

– Mineralocorticoids – aldosterone – zona glomerulosa;
– Glucocorticoids – cortisol & corticosterone – zona fasciculata;
– Sex steroids – androgens – zona reticularis;

26
Q

adrenal medulla

A

Catecholamines:
– Epinephrine (adrenalin); &
– Nor-epineprhine (nor-adrenalin)

27
Q

catabolic hormones do what?

A

promote tissue breakdown. example glucocortecoids

28
Q

what is the dual role of the adrenal gland?

A

Epinephrine secreted by the adrenal medulla stimulates glyconolysis. Then Cortisol - a glucocorticoid - is released from the adrenal cortex. this makes glucose from amino acids and glycerol.