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Respiratory Pharma > Muscarinic Antagonists > Flashcards

Muscarinic Antagonists Flashcards

1
Q

Examples

A

Ipratropium (SAMA)

Tiotropium (LAMA)

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2
Q

MoA

A

M3 muscarinic cholinoceptors on airway smooth muscle cells
Antagonist
Prevents activation of Gq proteins in the PS response
Reduces bronchospasm + mucous secretion

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3
Q

Indications

A

Maintenance COPD Tx

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4
Q

ADR

A

Dry Mouth

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5
Q

Prescribing Advice

A

Inhaled to reduce systemic SE

X Prostatic hyperplasia, Angle closure glaucoma

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Respiratory Pharma (6 decks)

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