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Respiratory Pharma > Beta2 Adrenoceptor Agonists > Flashcards

Beta2 Adrenoceptor Agonists Flashcards

1
Q

Examples

A

Salbutamol (SABA)

Salmeterol (LABA)

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2
Q

MoA

A

Beta 2 Adrenoceptor on airway smooth muscle cells
Agonist
Activate Gs Protein to activate adenylate cyclase
Produce cAMP that phosphorylates myosin light chain kinase and reduces [Ca2+]
Bronchodilatation

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3
Q

Indications

A

Acute Relief of Sx

Prophylaxis of asthma

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4
Q

ADR

A

Fine tremor of hands
Dysrhythmia
Hypokalaemia

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5
Q

Prescribing Advice

A

Inhaled to reduce systemic side effects

X CVD

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Respiratory Pharma (6 decks)

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