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Respiratory Pharma > Corticosteroids > Flashcards

Corticosteroids Flashcards

1
Q

Examples

A 
Beclametasone
Budesonide
Prednisolone
Hydrocortisone
Dexamethasone
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2
Q

MoA

A 
Cytosolic glucocorticoid receptor
Agonist
Alters DNA expression
Inhibits T-cell activation
Prevents inflammation via inhibiting phospholipase A2, COX-2, Cytokine, IgE formation
Inhibits IL-2 --> T-cell activation
Increase lipocortin
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3
Q

Indications

A 
1st Line Asthma
Prophylaxis
Inflammation
Hypocortisolism
(replacement)
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4
Q

ADR

A 
Oropharyngeal candidiasis
Growth retardation
Adrenal suppression
HTN
Bruising
Moonface and Buffalo Hump
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Respiratory Pharma (6 decks)

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