mung bean sprouts Flashcards

1
Q

main cause of hair loss that it targets

A

lack of communication between different types of cells in hair follicle

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2
Q

counteracts this

A

negative effect of DHT on hair follicle

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3
Q

where does DHT come from

A

testosterone interaction with 5-alpha-reductase enzyme, which is located in hair follicle oil glands

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4
Q

what is the primary cause of male patterned baldness (not the level of testosterone circulating)

A

level of DHT binding to receptors in scalp follicles

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5
Q

what actually happens to cause mpb

A

follicles become miniaturized
(large terminal hairs–>fine vellus-like hairs)
anagen phase is reduced, reducing anagen:telogen ratio
affected hairs cycle more quickly–>more follicles in resting phase

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6
Q

principle function of active

A

stimulate positive growth factors and genetic messages

promotes both anagen and telogen phase

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7
Q

role of flavonoids in the active

A

inhibitor of 5-alpha-reductase

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8
Q

mechanism of action

A

phytonutrients re-balance hair follicle cycling

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9
Q

in vitro testing shows increased production of ______ to ________

A

IGF1
SMC3
BMP4
PDGFA

–>restore healthy hair follicle cycling

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10
Q

clinical studies show

A

improvement of hair density
increase of active hair follicles
after 28 days

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11
Q

extract has been tested at

A

1%

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12
Q

IGF1 stands for

A

Insulin growth factor 1

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13
Q

PDGFA stands for

A

Platelet derived growth factor A

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14
Q

BMP4 stands for

A

Bone Morphogenetic Protein 4

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15
Q

SMC3 stands for

A

Structural maintenance of chromosome 3

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16
Q

function of IGF1

A

facilitate maintenance of hair follicle in anagen phase

17
Q

function of BMP4

A

act on DP cells

control HFSC and TAC to control proliferation and differentiation

18
Q

function of PDGFA

A

stimulate proliferation/differentiation of dermal mesenchymal cells that may contribute to formation of dermal papilla