MTB 5 (Endo, Infectious) Flashcards
Common findings in Infants of DM mothers
Macrosomia
Small Left Colon Syndrome
Cardiac abnormalities
Renal Vein thrombosis
Metabolic findings in IDM
Hypoglycemia
Hypocalcemia
Hypomagnesemia
Hyperbilirubinemia
Cardiac changes in IDM and management
Asymmetric septal hypertrophy due to obliterated LV lumen -> Decreased CO
Dx: EKG and Echo
Tx: beta blockers, IVF
Initial management of NB of diabetic mother w/shaking, holosystolic murmur, elevated BR
Check Blood sugar level
IDMs have high glucose levels
Upon delivery -> maternal glucose gone
Infants continue to make insulin = blood sugar levels drop
MC presentation of CAH
Hypotensive child w/severe electrolyte abnormalities
Girls - ambiguous genitalia, inappropriate facial hair, virilization, menstrual abnormalities
Electrolyte changes seen with CAH
HypoNatremia
HyperKalemia
HypoChloremia
Hypoglycemia
Decreased Aldosterone and cortisol
How is CAH diagnosed
Serum electrolytes
Increased 17-OH progesterone
Infants to mothers with Graves
If post thyroidectomy - Grave’s TSI levels increase to 500x normal after thyroidectomy
IgG autoabs cross placenta causing thyrotoxicosis in fetus and neonate
Irritability or lethargy suggest
Meningitis
MCC of neonatal sepsis
Pneumonia
Meningitis
Signs and Sx’s of neonatal sepsis
Poor oral intake Irritability Hypo/hyperthermia Resp distress Jaundice Vomiting Bulging fontanelles
How does infant botulinism present
Descending flaccid paralysis
BL bulbar palsy - ptosis, sluggish pupillary response to light, poor suck/gag reflex, drooling, constipation
Cause of infant botulinism - not honey
Increased incidence in Cali, Penn, Utah from soil
Botulinim spores from environment/dust = spore ingestion
Neonatal Toxoplasmosis Presentation
Chorioretinitis
Hydrocephalus
Multiple ring enhacing lesions - CT
Neonatal Syphilis Presentation
Rash on palms and soles Snuffles Frontal bossing Hutchinson teeth Saddle nose
Neonatal Rubella
PDA Blueberry muffin rash Cataracts Deafness HSM Thrombocytopenia