MSRA: Chronic Lymphocytic Leukaemia Flashcards

1
Q

Which cells proliferate causing CLL?

A

B lymphocytes

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2
Q

What are the symptoms of CLL?

A
Often asymptomatic but detected on FBC with lymphocytosis
Susceptibility to infections
Enlarged lymph nodes (painless)
Anaemia
Thrombocytopenia
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3
Q

What is seen on a peripheral blood film in CLL?

A

Smudge/smear cells (fragile lymphocytes which disintegrate during preparation of the slide

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4
Q

What are the FBC results in CLL?

A

Lymphocytosis

Anaemia and thrombocytopenia

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5
Q

What are the complications of CLL?

A

Bacterial and viral infections
Hyperviscosity syndrome
Autoimmune disease (autoimmune haemolytic anaemia)
Transformation to lymphoma

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