MSRA: Chronic Lymphocytic Leukaemia Flashcards
1
Q
Which cells proliferate causing CLL?
A
B lymphocytes
2
Q
What are the symptoms of CLL?
A
Often asymptomatic but detected on FBC with lymphocytosis Susceptibility to infections Enlarged lymph nodes (painless) Anaemia Thrombocytopenia
3
Q
What is seen on a peripheral blood film in CLL?
A
Smudge/smear cells (fragile lymphocytes which disintegrate during preparation of the slide
4
Q
What are the FBC results in CLL?
A
Lymphocytosis
Anaemia and thrombocytopenia
5
Q
What are the complications of CLL?
A
Bacterial and viral infections
Hyperviscosity syndrome
Autoimmune disease (autoimmune haemolytic anaemia)
Transformation to lymphoma