MSRA: Acute Myeloid Leukaemia

Question 1

Which cells proliferate in acute myeloid leukaemia?

Answer 1

Myeloid blast cells

Question 2

What are the risk factors for AML?

Answer 2

Increasing age
Benzene exposure
Previous chemotherapy
Radiation exposure
Myeloproliferative neoplasm

Question 3

What are the symptoms of AML?

Answer 3

Anaemia - fatigue, pallor, dizziness
Thrombocytopenia - petechiae and purpura
Bone pain
Abdominal pain and distention 
Gingivitis

Question 4

What are the most common sites for infiltration in AML?

Answer 4

Liver
Spleen
Gums

Question 5

What are the blood results in AML?

Answer 5

Anaemia
Thrombocytopenia
High WCC due to detection of blast cells
Auer rods and blast cells on peripheral film