MSK disease

Question 1

acute monoarthritis/oligoarthritis

Answer 1

septic arthritis
gout
reactive arthritis

Question 2

chronic inflammatory polyarthritis

Answer 2

RA
psoriatic arthritis
chronic tophaceous gout

Question 3

spondyloarthropathy

Answer 3

ank spond

Question 4

septic arthritis

Answer 4

infection unless proven otherwise (8-27%)
aspirate prior to A/B if at all possible
local guidance for A/B
not treating leads to rapid joint destruction and significant (11%) mortality
can be polyarticular in 10% of cases
usually involves hip or knee

Question 5

predicting septic arthritis

Answer 5

fever
WCC
CRP
joint tendrness/restriction

Question 6

risk factors for septic arthritis

Answer 6

overlying/penetrating infection
prosthesis/surgery
age
diabetes
RA
HIV
corticosteroids

Question 7

gout

Answer 7

urate crystals
RF:
alcohol
diet
renal failure
chemo
dehydration
psoriasis
haemolysis
negatively birefringent

Question 8

pseudogout

Answer 8

calcium pyrophospahte crystals
self limiting
elderly or metabolic disease
often wrist or knee
positively birefringent

Question 9

RA

Answer 9

autoimmune disorder

articular clinical phenotype, but is a multisystem disease involving lung, skin, eyes, CV system

Question 10

risk factors for RA

Answer 10

presence of anti-CCP antibodies
FH (PTPN22)
smoking

Question 11

ankylosing spondylitis

Answer 11

sacroiliitis
HLA-B27 gene
association with other seronegative diseases (psoriasis, colitis, uveitis)
bamboo spine

Question 12

OA

Answer 12

heberden’s - DIPs

Bouchard’s - PIPs