MSK Flashcards
What would symmetrical small joint swelling suggest?
Rheumatoid arthritis
Name the categories of inflammatory arthritis?
Seropositive
Seronegative
Infectious
Crystal induced
Name the seropositive arthritis?
RA Lupus Sclerodema Vasculitis Sjorgens
Name the seronegative arthritis?
Ankylosing spondylitis
Psoriatic arthritis
Reactive arthritis
Inflammatory bowel disease arthritis
What is the ‘S factor’?
Stiffness
Swelling
Squeezing is painful = an inflammatory arthritis
How do we diagnose RA?
History and clinical exam
Inflammatory markers (CRP,plasma viscosity)
Autoantibodies
Imaging
Which auto-antibody is most specific for RA?
Anti-CCP antibody
Treatment for RA?
Early recognition and diagnosis
Early treatment with DMARDS
Tight control with target of remission Patient education
What is the description of uric acid crystals as seen under polarised light microscopy?
Negatively birefringent, needle shaped crystals
2 main crystal arthropathies?
Gout Pseudogout (Calcium pyrophosphate deposition disease)
How does gout present?
Intense pain, redness and swelling
How do CPPD uric acid crystals appear?
Rhomboid shaped and weakly positive birefringent
Name key features of OA on X-ray?
Loss of joint space Osteophyte formation Subchondral sclerosis Subchondral cysts - remember LOSS
Which type of arthritis has periarticular erosions?
RA
In a patient with fibromyalgia, what blood abnormalities would you expect to see?
No abnormality
Would morphine sulfate be a suitable treatment for fibromyalgia?
NO