MSK Flashcards
management of OA
- topical analgesia + lifestyle factors
- Paracetamol
- NSAID plus PPI (eg Naproxen 250-500mg BD)
- Corticosteroid intraarticular injection
- Surgery
management of RA
- DMARD (Methotrexate)
- Adjunct corticosteroid (Prednisolone) or NSAID (eg Naproxen)
If giving steroid long term, supplement with Vitamin D and calcium) - DMARD Combination therapy e.g. Hydroxychloroquine or Sulfalazine
- Biologic Agent (e.g. TNF alpha inhibitors, etanercept, infliximab, adalimumbab)
management of Ank Spond
- NSAID plus physiotherapy and stretching and exercise advice
eg Naproxen 500mg BD - TNF alpha inhibitor eg alalimumbab , etanercept
Fibromyalgia Management
- Lifestyle and relaxation techniques
TCAs eg Amitriptyline
what are the features of fibromyaligia?
- chronic pain
- diffuse tenderness on examination ( need >11/18 tender points)
- fatigue unrelieved by rest
- sleep and mood disturbance
- abnormal sensations
- sensitivity to bright colours , loud noises and strong odours
- headaches
what is the most accurate movement for measuring hip function and hip pain?
internal rotation
what are red flags in the history of hip pain in a child?
- night pain, night sweats, weight loss = Acute lymphoblastic leukaemia
- fever, holding leg ABDUCTED = septic arthritis
- Fever, NON WEIGHT BEARING= osteomyelitis of femur pelvis
- changeable , unclear or unusual history= NON ACCIDENTAL INJURY
what are some causes of hip pain in a child?
- fracture
- developmental dysplasia of the hip (aka congenital dislocation)
- Girls>Boys, Congenital, skin folds and buttock flattening, Born with it. - Transient synovitis (follows urti)
- juvenile idiopathic arthritis
- Perthes disease (Boys 4-8 yrs) AVN and remodelling of femoral epiphyses
- Slipped upper femoral epiphyseal
what are the signs of cauda equina?
- bladder/bowel dysfunction
- bilateral sciatica
- saddle anaesthesia
MRI scan these patients
back pain red flags
- weight loss, fever, systemic illness
- cauda equina symptoms
- severe tearing pain : AAA?also exclude other abdo causes
- immunosuppressed, IVDU , corticosteroid patients
what is a pathological fracture? and what are some causes
a fracture through abnormal bone
e.g. osteoporosis, osteomalacia, osteopenia, bony mets, infections, bony metabolic diseases, secondary to medications
how would you manage an open fracture?
- Primary survey (ABCDE)
- Secondary survey (look for further injuries)
- Remove gross contamination
- Photograph the wound
- Place a saline soaked gauze over the wound and put limb in a splint
- give iv prophylactic antibiotics
- list for theatre within 24 hours for debridement and washout and stabilization
Imaging also chest abdo pelvis x ray
signs of compartment syndrome
Pain, especially on movement (even passive)
Parasthesiae
Pallor may be present
Arterial pulsation may still be felt as the necrosis occurs as a result of microvascular compromise
Paralysis of the muscle group may occur
what is compartment syndrome
Compartment Syndrome is when the pressure within a fascial compartment exceeds the perfusion pressure within the compartment, causing ischaemia of the tissues within the compartment.
what would you do if you suspected compartment syndrome
- Review neurovascular status of limb
- review analgesia and release any dressings or casts which might be increasig the pressure
- position limb at level with the heart
- contact senior, as they may need emergency fasciotomy
what are some factors which may cause mal union or non union
local factors: blood supply, infection, stability, pattern
systemic factors: smoking, diabetes, corticosteroids, HIV, diet, NSAIDs
what is the most senstitive clinical sign for diagnosing compartment syndrome
pain on passive stretch
x ray features of gout
- gouty tophi
- punched out lesions
- soft tissue swelling
treatment of gout
acute: NSAIDs and Colchicine
long term: Allopurinol
which compartment of the leg is most commonly affected by compartment syndrome?
anterior compartment
what is pagets disease of the bone?
occurs in people >55 years
focal bone resorption followed by excessive and chaotic bone deposition
affects in order spine, skull, pelvis, femur
ALP raised
abnormal thickened sclerotic bone on x ray
treat with Bisphosphonates
Raynauds disease
- who gets it
- what is it
- how to treat it
typically presents in females under the age of 30
symmetrical attacks
spasms of arterioles can lead to diminshed blood supply to the affected area causing them to turn white or even blue
typically affects the hands and feet
treated with calcium channel blocker (Nifedipine)
Raynauds Phenomenon
secondary to CTD
what features suggest this?
typically occuring secondary to CTDs features which indicate raynauds from CTD: -presenting >40 yrs -systemic features -asymmetry -rashes -auto antibodies
what are the small vessel vasculitides
Granulomatosis Polyangiitias
Eosinophillic Granulomatosis Polyangiitis
Microscopic polyangiitis
Henoch Schonlein purpura (IgA mediated)
medium vessel vasculitides
Kawasaki disease (paediatrics, strawberry tongue, treat with aspirin) Polyarteritis nodosa (necrotising inflammation, associated with hep b and livedo reticularis)
large vessel vasculitides
Takayasu
Giant Cell Arteritis
microscopic polyangiitis
Microscopic polyangiitis is a small-vessel ANCA vasculitis
Features
renal impairment: raised creatinine, haematuria, proteinuria
fever
other systemic symptoms: lethargy, myalgia, weight loss
rash: palpable purpura
cough, dyspnoea, haemoptysis
mononeuritis multiplex
what is nephrotic syndrome
hypoalbuminaemia, oedema, heavy proteinuria (>3-5g/24hrs), hyperlipidaemia, lipiduria
what is nephritic syndrome?
haematuria, oliguria, hypertension, proteinuria (>2g/24hrs), oedema ureamia
symptoms of SLE
- raynauds
- mouth ulcers
- rash on cheeks
- weight loss
- low grade fever
- fatigue
- joint pain and swlling
- oedema
- pleural effusion
- pericarditis/pericadial effusion
- loss of appetite
- photosensitivity
what is the antibody for SLE
Anti-ds DNA , Smith , nRNP
what is the antibody for Sjorgens syndrome?
Ro(SSA) La (SSB)
what is the antibody for subacute cutaneous lupus erythematosus (SCLE)
Ro (SSA) La(SSB)