MSK

Question 1

Avascular necrosis

Answer 1

Associated with high dose glucocorticoid use

Crescent sign on CXR which indicates subcondral collapse

Question 2

Osteosarcoma

Answer 2

Most common tumor associated with Paget’s

Tumor pain doesn’t respond to OTC analgesics

Question 3

Molluscum contagiosum

Answer 3

Umbilicated, flesh colored papules on skin/mucus membranes
Caused by poxvirus
Eosinophilic cytoplasmic inclusions (molluscum bodies)

Question 4

Nerve/muscle deficiency causing winged scapula?

Answer 4

Long thoracic nerve

Serratus anterior

Question 5

Osteomalacia

Answer 5

Decreased mineralization of osteoid
Vit D def/malabsorption (after surgery)

(osteoporosis is reabsorption of cortical and trabecular bone)

Question 6

Paget’s disease of the bone

Answer 6

Related to osteosarcoma

Abnormal lamellar bone formation

Question 7

Larengeal nerves

Answer 7

Internal: supraglottic sensation
External: cricothyroid
Recurrent: all intrinsic muscles of larynx (anything with arytenoid in the name)

Question 8

Pemphigus vulgaris

Answer 8

Against desmosomes (desmoglein 3 and 1)
Intraepidermal cleavage/acanthyolysis/tombstone cells
Netlike IgG
Flaccid bulla with oral/mucosal involvement

Question 9

Bullous phemphigoid

Answer 9

Against hemidesmosomes (BP antigens 1 and 2)
Subepidermal cleveage
Linear IgG
Tense bulla with no oral/mucosal