MSK Flashcards

1
Q

Differential diagnosis for epiphyseal lesions

A

Chondroblastoma IS AGE

Chondroblastoma
I: infection or infarction
S: solitary/simple bone cyst
A: aneurysmal bone cyst
G: giant cell tumour or geode
E: enchondroma

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2
Q

Differentials for multiple lytic bone lesions in an adult

A

Metastases (thyroid, renal. Lung and breast may be mixed)
Multiple myeloma
Lymphoma

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3
Q

Differentials for lytic bone lesions in a child

A

Langerhans cell histiocytosis
Fibrous Dysplasia
Chronic recurrant multifocal osteomyelitis (CRMO)

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4
Q

Differentials for sequestrum

A

Osteomyelitis
Langerhans cell histiocytosis
Osteoid Osteoma

Additional:
Lymphoma
Fibrosarcoma

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5
Q

Differentials for periosteal reaction in the newborn

A

Physiologic periosteal reaction
Trauma
Infection

Additional:
Prostaglandin therapy
Infantile cortical hyperostosis (Caffeys disease)

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6
Q

Differentials for rugger jersey spine

A

Renal Osteodystrophy
Osteopetrosis
Pagets

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7
Q

Differentials for bilateral symmetric sacroilitis

A

Ankylosing Spondylitis
Inflammatory bowel disease
Rheumatoid arthritis

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8
Q

Differentials for unilateral or asymmetric sacroiliitis

A

Psoriatic arthritis
Reactive Arthritis
Septic Arthritis

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9
Q

Differentials for proximal arthropathy affecting primarily the metacarpophalangeal joints

A

Rheumatoid arthritis
Calcium pyrophospate desposition disease (CPPD)
Collagen vascular disease (SLE)

Additional:
Hameochromatosis

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10
Q

Differentials for distal arthropathy affecting the interphalangeal joints

A

Osteoarthritis
Erosive osteoarthritis
Psoriatic arthritis

Additional:
Reactive arthritis
Rheumatoid arthritis

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11
Q

Differentials for erosive arthropathy involving the foot

A

Rheumatoid arthritis
Gout
Reactive arthritis

Additional
Psoriatic arthritid

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12
Q

Differentials for distal clavicular erosion/resorption

A

Post-traumatic
Rheumatoid arthritis
Hyperparathyroidism

Additional
Scleroderma
Infection

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13
Q

Differentials for vertebral plana in adults

A

Multiple myeloma
Metastases
Trauma

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14
Q

Differentials for vertebral plana in a child

A

Langerhans cell histiocytosis (most common)
Leukaemia/lymphoma
Osteomyelitis

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15
Q

Differentials for wormian bones

A

Idiopathic
Osteogenesis Imperfecta
Cleidocranial dysostosis

Additional
Down syndrome
Metabolic disease (hypothyroidism, rickets)

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16
Q

Differentials for Madelung deformity

A

Idiopathic Madlung deformity
Post-traumatic
Skeletal dysplasias

17
Q

Differentials for osseous lesion with fluid-fluid levels

A

Aneurysmal bone cyst
Unicameral bone cyst
Telangiectatic osteosarcoma

Additional
Fibrous dysplasia
Chondroblastoma

18
Q

Differentials for medullary/chondroid lesion

A

Enchondroma
Chondrosarcoma
Bone infarct

Additional:
Chronic osteomyelitis

19
Q

Differentials for acro-osteolysis (terminal tuft resoprtion)

A

Hyperparathyroidism
Scleroderma
Trauma

Additional
Psoriasis
Hajdu-Cheney syndrome

20
Q

Differentials for diffusely increased bone density

A

Metabolic disorders
Osteoblastic metastases
Haematologic disorders

Additional
Pagets
Osteopetrosis

21
Q

Differentials for loose bodies

A

Synovial osteochondromatosis
Pigmented villonodular synovitis (PVNS)
Rice bodies

22
Q

Differentials for expansile bone lesion in a child

A

Fibrous dysplasia
Bone cyst (unicameral cyst/ABC)
Enchondroma

Additional:
Langerhans
Ewings sarcoma (associated with soft tissue mass)
Metastasis

23
Q

Differentials for ivory vertebral body

A

Osteoblastic mets
Pagets
Lymphoma

Additional:
Mastocytosis
Myeloma

24
Q

Differentials for periarticular soft tissue calcifications

A

Calcinosis of renal failure
Myositis Ossificans
Arthopathy with calcified soft tissue nodule

Additional:
Scleroderma
Soft tissue sarcoma
Tumoral calcinosis

25
Q

Differentials for benign expansile lytic lesion

A

Fibrous dysplasia
Unicameral bone cyst
Aneurysmal bone cyst

Additional:
Giant cell tumour
Eosinophilic granuloma

26
Q

Differentials for multiple sclerotic foci within the pelvis

A

Osteopoikilosis
Metastatis disease (breast/prostate)
Pagets

27
Q

Differentials for vertebral body wedge fracture

A

Traumatic fracture (involves superior endplate upper lumar spine)
Insufficiency fracture (spares posterior elements)
Pathologic fracture (can involve posterior elements)

28
Q

Differentials for epiphyseal/epiphyseal equivalent lucent lesion

A

Chondroblastoma (usually before skeletal maturity)
Giant cell tumours (after skeletal maturity)
Langerhans (can cross open growth plate)

Additional:
Intraosseous ganglion cyst