MSK Flashcards
Differential diagnosis for epiphyseal lesions
Chondroblastoma IS AGE
Chondroblastoma
I: infection or infarction
S: solitary/simple bone cyst
A: aneurysmal bone cyst
G: giant cell tumour or geode
E: enchondroma
Differentials for multiple lytic bone lesions in an adult
Metastases (thyroid, renal. Lung and breast may be mixed)
Multiple myeloma
Lymphoma
Differentials for lytic bone lesions in a child
Langerhans cell histiocytosis
Fibrous Dysplasia
Chronic recurrant multifocal osteomyelitis (CRMO)
Differentials for sequestrum
Osteomyelitis
Langerhans cell histiocytosis
Osteoid Osteoma
Additional:
Lymphoma
Fibrosarcoma
Differentials for periosteal reaction in the newborn
Physiologic periosteal reaction
Trauma
Infection
Additional:
Prostaglandin therapy
Infantile cortical hyperostosis (Caffeys disease)
Differentials for rugger jersey spine
Renal Osteodystrophy
Osteopetrosis
Pagets
Differentials for bilateral symmetric sacroilitis
Ankylosing Spondylitis
Inflammatory bowel disease
Rheumatoid arthritis
Differentials for unilateral or asymmetric sacroiliitis
Psoriatic arthritis
Reactive Arthritis
Septic Arthritis
Differentials for proximal arthropathy affecting primarily the metacarpophalangeal joints
Rheumatoid arthritis
Calcium pyrophospate desposition disease (CPPD)
Collagen vascular disease (SLE)
Additional:
Hameochromatosis
Differentials for distal arthropathy affecting the interphalangeal joints
Osteoarthritis
Erosive osteoarthritis
Psoriatic arthritis
Additional:
Reactive arthritis
Rheumatoid arthritis
Differentials for erosive arthropathy involving the foot
Rheumatoid arthritis
Gout
Reactive arthritis
Additional
Psoriatic arthritid
Differentials for distal clavicular erosion/resorption
Post-traumatic
Rheumatoid arthritis
Hyperparathyroidism
Additional
Scleroderma
Infection
Differentials for vertebral plana in adults
Multiple myeloma
Metastases
Trauma
Differentials for vertebral plana in a child
Langerhans cell histiocytosis (most common)
Leukaemia/lymphoma
Osteomyelitis
Differentials for wormian bones
Idiopathic
Osteogenesis Imperfecta
Cleidocranial dysostosis
Additional
Down syndrome
Metabolic disease (hypothyroidism, rickets)