MSK Flashcards

1
Q

IT band sx and mx

A

tenderness 2-3cm above the lateral joint line
Common in runners

Management
activity modification and iliotibial band stretches
if not improving then physiotherapy referral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Red flags back pain

A

age < 20 years or > 50 years
history of previous malignancy
night pain
history of trauma
systemically unwell e.g. weight loss, fever
Thoracic back pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hip disclocation sx

A

shortened and internally rotated leg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Mx and complications of hip dislocation

A

A reduction under general anaesthetic within 4 hours to reduce the risk of avascular necrosis.

Sciatic or femoral nerve injury
Avascular necrosis
Osteoarthritis: more common in older patients.
Recurrent dislocation: due to damage of supporting ligaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

calcification of the articular cartilage dx

A

Pseudogout

Chondrocalcinosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Spinal stenosis

A

Usually gradual onset
Unilateral or bilateral leg pain (with or without back pain), numbness, and weakness which is worse on walking. Resolves when sits down. Pain may be described as ‘aching’, ‘crawling’.
Relieved by sitting down, leaning forwards and crouching down

Clinical examination is often normal

Requires MRI to confirm diagnosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Signs of scaphoid fracture

A

Point of maximal tenderness over the anatomical snuffbox
This is a highly sensitive (around 90-95%), but poorly specific test (<40%) in isolation
2. Wrist joint effusion
Hyperacute injuries (<4hrs old), and delayed presentations (>4days old) may not present with joint effusions.
3. Pain elicited by telescoping of the thumb (pain on longitudinal compression)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Infrapatella bursitis

A

associated with kneeling as seen in clergymen
Swelling and tenderness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Psoriatic arthritis sx

A

symmetric polyarthritis
very similar to rheumatoid arthritis
30-40% of cases, most common type
asymmetrical oligoarthritis: typically affects hands and feet (20-30%)

Dactylitis, sometimes described as ‘sausage fingers’

periarticular disease - tenosynovitis and soft tissue inflammation resulting in:
enthesitis: inflammation at the site of tendon and ligament insertion e.g. Achilles tendonitis, plantar fascitis
tenosynovitis: typically of the flexor tendons of the hands
dactylitis: diffuse swelling of a finger or toe
nail changes
pitting
onycholysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

X ray psoriatic arthritis

A

‘pencil-in-cup’ appearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Dermatomyositis sx

A

Skin features
photosensitive
macular rash over back and shoulder
heliotrope rash in the periorbital region
Gottron’s papules - roughened red papules over extensor surfaces of fingers

proximal muscle weakness +/- tenderness

ANA+
Anti Jo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Right-sided hip pain radiating to knee and joint instability, post THR

A

Aseptic loosening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

If UGI SE from alendronate

A

Change to risedronate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Acute mx of gout

A

NSAID
Colchicine - avoid if GFR <10
Oral steroids if others CI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SE of entanjrcept

A

Reactivation of TB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

AS mx

A

Ibuprofen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

AS XR

A

sacroiliitis: subchondral erosions, sclerosis
squaring of lumbar vertebrae
‘bamboo spine’ (late & uncommon)
syndesmophytes: due to ossification of outer fibers of annulus fibrosus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Clubfoot findings

A

Inverted + plantar flexed foot which is not passively correctable.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

PMR sx and mx

A

typically patient > 60 years old
usually rapid onset (e.g. < 1 month)
aching, morning stiffness in proximal limb muscles
ESR>40

Pred 15mg- 1 week then reassess

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Sjogren AB

A

Positive anti-Ro and anti-La antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Sjogren’s syndrome sx

A

dry eyes: keratoconjunctivitis sicca
dry mouth
vaginal dryness
arthralgia
Raynaud’s, myalgia
sensory polyneuropathy
recurrent episodes of parotitis

positive Schirmer’s test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Mx of hip fracture

A

Undisplaced Fracture:
internal fixation, or hemiarthroplasty if unfit.

Displaced Fracture:
arthroplasty (total hip replacement or hemiarthroplasty) to all patients with a displaced intracapsular hip fracture
total hip replacement is favoured to hemiarthroplasty if patients:
were able to walk independently out of doors with no more than the use of a stick and
are not cognitively impaired and
are medically fit for anaesthesia and the procedure.

stable intertrochanteric fractures: dynamic hip screw

if reverse oblique, transverse or subtrochanteric fractures: intramedullary device

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

AS features

A

reduced lateral flexion
reduced forward flexion - Schober’s test
Pain at night
Reduced chest expansion

Anterior uveitis
Aortic regurgitation
Achilles tendonitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Prepatellar bursitis

A

Associated with more upright kneeling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Bone protection if started on long term steroids

A

Immediate bisphosphonate prescription

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Phalen sign

A

Flexion of wrist produces carpal tunnel signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Sickle cell osteomyelitis organism

A

Salmonella- noon typhi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

When is colchicine CI

A

he BNF advises to reduce the dose by up to 50% if creatinine clearance is less than 50 ml/min and to avoid if creatinine clearance is less than 10 ml/min.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Mx of prolapsed disc

A

irst-line is NSAIDs +/- proton pump inhibitors rather than using neuropathic analgesia (e.g. duloxetine)
if symptoms persist e.g. after 4-6 weeks) then referral for consideration of MRI is appropriate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

High risk group of fragility fractures

A

Age >75
Glucocorticoid therapy
(People who are taking high doses of oral corticosteroids (more than or equivalent to prednisolone 7.5 mg daily for 3 months or longer)
Previous hip/vertebral fractures
Further fractures on treatment
High risk on FRAX scoring
T score <-2.5 after treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

When should you continue/stop bisphosphonates

A

Any high risk- continue indefinitely

Low risk- repeat DEXA, 2 year break if >-2.5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Taking bisphosphonates

A

swallowed with plenty of water while sitting or standing on an empty stomach at least 30 minutes before breakfast (or another oral medication); the patient should stand or sit upright for at least 30 minutes after taking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Limited scleroderma sx

A

Raynaud’s may be the first sign
scleroderma affects face and distal limbs predominately
associated with anti-centromere antibodies
a subtype of limited systemic sclerosis is CREST syndrome: Calcinosis, Raynaud’s phenomenon, oEsophageal dysmotility, Sclerodactyly, Telangiectasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Diffuse cutaneous systemic sclerosis

A

scleroderma affects trunk and proximal limbs predominately
associated with anti scl-70 antibodies
the most common cause of death is now respiratory involvement, which is seen in around 80%: interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH)
other complications include renal disease and hypertension
patients with renal disease should be started on an ACE inhibitor
poor prognosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Hydroxycholorqiune SE

A

bull’s eye retinopathy - may result in severe and permanent visual loss
Corneal opacities

36
Q

Mx of GCA with temporal arteritis

A

Oral pred
IV if visual loss

37
Q

Allopurinol during gout attacks

A

If already on it- continue

Just do not start on it on first attack

38
Q

X ray sign of rheumatoid

A

loss of joint space
juxta-articular osteoporosis
soft-tissue swelling
periarticular erosions
subluxation

39
Q

Tx of osteoporosis in stage 4 CKD

A

Denosumab
BP CI

40
Q

Movement making lateral/medial epicondylitis worse

A

Lateral epicondylitis: worse on resisted wrist extension/suppination whilst elbow extended

Medial -wrist flexion and pronation

41
Q

Medications causing gout

A

diuretics: thiazides, furosemide
ciclosporin
alcohol
cytotoxic agents
pyrazinamide

42
Q

Nerve root of triceps

A

Main C7

43
Q

Osteosarcoma features

A

x-ray shows Codman triangle (from periosteal elevation) and ‘sunburst’ pattern
metaphyseal region of long bones prior to epiphyseal closure

44
Q

Ewing sarcoma

A

x-ray shows ‘onion skin’ appearance

45
Q

Baker Cyst

A

Foucher’s sign describes the increase in tension of the Baker’s cyst on extension of the knee.

More likely to develop in patients with arthritis or gout and following a minor trauma to the knee

46
Q

Dermatomyositis features

A

Skin features
photosensitive
macular rash over back and shoulder
heliotrope rash in the periorbital region
Gottron’s papules - roughened red papules over extensor surfaces of fingers

Other features
proximal muscle weakness +/- tenderness
Raynaud’s

47
Q

Radial tunnel syndrome

A

tenderness distal to the common extensor origin in comparison to lateral epicondylitis where there is pain over the common extensor origin. It is most common in gymnasts, racquet players and golfers who frequently hyperextend at the wrist or carry out frequent supination/pronation. Patients can also complain of hand paraesthesia or aching at the wris

48
Q

Sulfasalazine SE

A

Oliospermia
Rashes

49
Q

Gold SE

A

Proteinuria

50
Q

Antiphospholipid sx bloods

A

Antiphospholipid syndrome leads to a raised APTT and normal PT and can result in thrombocytopenia.

51
Q

Nerve likely to be injured ion TKR

A

Common Peroneal nerve

52
Q

Etanercept SE

A

Demyelination
Reactivation of TB

53
Q

Methotrexate SE

A

Myelosuppression
Liver cirrhosis
Pneumonitis

54
Q

Mx of Raynaud’s

A

Oral nifedipine

55
Q

What do you have to do before giving bisphosphonates

A

Hypocalcemia/vitamin D deficiency should be corrected before giving bisphosphonates

56
Q

Drug induced lupus causes

A

Proncainamide
Hydralazine

57
Q

Plantar fascitis sx

A

The pain is usually worse around the medial calcaneal tuberosity.

Pain is worse when you ask them to walk on their toes.

58
Q

L3 vs L4 compression

A

L3 nerve root compression
Sensory loss over anterior thigh
Weak hip flexion, knee extension and hip adduction
Reduced knee reflex
Positive femoral stretch test

L4 nerve root compression Sensory loss anterior aspect of knee and medial malleolus
Weak knee extension and hip adduction
Reduced knee reflex
Positive femoral stretch test

59
Q

Pencillamine SE

A

Proteinuria
Exacerbation of MG

60
Q

Femeroacetabular impingement

A

presents with hip/groin pain worse on prolonged sitting and associated with snapping, clicking or locking of the hip. There is an association between FAI and prior hip pathology eg Perthes in childhood.

61
Q

Adhesive capsulitis sx

A

External rotation (on both active and passive movement) is classically impaired

62
Q

Mx of RA false

A

IM or oral pred

63
Q

Drug induced lupus AB

A

Antihistone

64
Q

Cough, dyspnoea and fever on methotrexate

A

Drug induced pneumonitis

65
Q

Greater trochanteric pain syndrome

A

Pain and tenderness over the lateral side of thigh
Most common in women aged 50-70 years
(trochanteric bursitis)

66
Q

Sjogrens AB

A

Anti Ro

67
Q

Dermatomyositis AB

A

Anti Jo

68
Q

Myxoid cyst

A

digital mucous cysts, are benign lesions that typically occur on the fingers or toes, particularly around the nail bed.
Associated With OA

69
Q

Risk of stress factures

A

Inadequate calories
Menstrual irregularities
Increased/new intensity sports

70
Q

Dupuytrens contracture causes

A

manual labour
phenytoin treatment
alcoholic liver disease
diabetes mellitus
trauma to the hand

71
Q

Tx of reactive arthritis

A

NSAIDs

72
Q

Test before adalimumab

A

CXR

73
Q

Pancytopaenia with methotrexate cause

A

Taking with trimethoprim

74
Q

CKD biochem on Ca, P , ALP

A

High P, high ALP, high PTH

75
Q

Chronic fatigue diagnosis

A

Diagnosed after at least 3 months of disabling fatigue affecting mental and physical function more than 50% of the time in the absence of other disease which may explain symptoms

76
Q

Adivse post hip replacement

A

avoiding flexing the hip > 90 degrees
avoid low chairs
do not cross your legs
sleep on your back for the first 6 weeks

77
Q

Mx of achilles tendonitis

A

Achilles tendonitis management: rest, NSAIDs, and physio if symptoms persist beyond 7 days

78
Q

Poor prognostic features of RA

A

rheumatoid factor positive
anti-CCP antibodies
poor functional status at presentation
X-ray: early erosions (e.g. after < 2 years)
extra articular features e.g. nodules
HLA DR4
insidious onset

79
Q

Reactive arthritis sx

A

Arthritis
Eye pain
Dactylitis
Dysuria

80
Q

Skin disorder with antiphospholipid syndrome

A

Lived reticularis

81
Q

Osteomalacia sx

A

Low Ca, P, raised ALP

Proximal myopathy

82
Q

If allergic to aspirin which RA drug are you likely allergic to

A

Sulfalazine

83
Q

Inversion ligament damage

A

anterior talofibular ligament is the most commonly sprained

84
Q

Antibodies associated with each condition

A

A: Anti-centromere antibodies
Limited cutaneous systemic sclerosis (CREST Syndrome)

B: Anti-Scl70 antibody
Diffuse systemic sclerosis
(Scleroderma)

C: Anti-Jo antibodies
-myositis
e.g. Polymyositis, dermatomyositis

D: Anti-mitochondrial antibodies
Primary biliary cholangitis (PBC)

E: Anti-neutrophil cytoplasmic antibodies (ANCA)
Small vessel vasculitis

F: Anti-nuclear antibodies (ANA)
Autoimmune conditions
e.g. SLE, RA, Sjogrens

G: Anti-phospholipid antibodies
Blood clots & Miscarriages

H: Anti-Ro antibodies
SLE or Sjogrens

I: Parietal cell antibodies
Pernicious anaemia

J: Anti-gliadin antibodies
Coeliac disease

K: Anti-histone antibodies
Drug-induced lupus

85
Q
A
86
Q
A